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短指畸形,史前鲁珀特王子港可能存在的一种遗传性异常。

Brachydactyly, a possible inherited anomaly at prehistoric Prince Rupert Harbour.

作者信息

Cybulski J S

机构信息

Archaeological Survey of Canada, Canadian Museum of Civilization, National Museums of Canada, Ottawa, Ontario.

出版信息

Am J Phys Anthropol. 1988 Jul;76(3):363-76. doi: 10.1002/ajpa.1330760309.

DOI:10.1002/ajpa.1330760309
PMID:3046372
Abstract

Disproportionately short metacarpals or metatarsals in eight burial skeletons and three unusually short metapodials recovered as disturbed bones were identified in a 1500 B.C. to A.D. 500 skeletal series from eight archeological sites of the north mainland coast of British Columbia, Canada. At least ten people were affected from four sites for a minimum series frequency of 5.2%. Various factors clinically implicated in the occurrence of brachymetapody were investigated to account for the anomaly. Context-sensitive information suggested that trauma, infarction or infection, and individual or family-related malformation syndromes were unlikely possibilities. Some modern population data suggest that the series frequency was unusually high, particularly for fourth metatarsal involvement, the most commonly affected bone. Modern pedigree interpretations, ethnohistoric inferences, and the archeological contexts of the affected burial skeletons and site samples provide a framework for concluding that brachymetapody in the series was more likely due to the inheritance of an essentially isolated anomaly.

摘要

在加拿大不列颠哥伦比亚省北大陆海岸的八个考古遗址出土的一个公元前1500年至公元500年的骨骼系列中,鉴定出八具墓葬骨骼中有不成比例的短掌骨或跖骨,以及作为扰动骨骼回收的三根异常短的掌骨或跖骨。至少有来自四个遗址的十个人受到影响,最低系列频率为5.2%。研究了临床上与短掌(跖)骨发生有关的各种因素,以解释这种异常现象。与背景相关的信息表明,创伤、梗死或感染以及个体或家族相关的畸形综合征不太可能。一些现代人群数据表明,该系列频率异常高,尤其是第四跖骨受累,这是最常受影响的骨骼。现代谱系解释、民族历史推断以及受影响墓葬骨骼和遗址样本的考古背景提供了一个框架,据此可以得出结论,该系列中的短掌(跖)骨更可能是由于一种基本孤立的异常的遗传。

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