Research Institute for Tropical Medicine, Muntinlupa City, Philippines.
Research Institute for Tropical Medicine, Muntinlupa City, Philippines.
Vaccine. 2018 Dec 14;36(51):7888-7893. doi: 10.1016/j.vaccine.2018.08.046. Epub 2018 Nov 19.
With the availability of new and existing rotavirus vaccines, credible and reliable data on burden of rotavirus-associated disease are needed to enable evidence-based decision making regarding the introduction of rotavirus vaccines. The national rotavirus surveillance program in the Philippines, a sentinel-based surveillance, was established in 2012 to determine the proportion of laboratory-confirmed rotavirus cases among children under five years with acute gastroenteritis and to describe the geographic distribution and molecular epidemiology of rotavirus in the country. During 2013 to 2015, rotavirus infection was the cause of acute gastroenteritis among children under five years admitted to hospitals or evaluated in emergency rooms, constituting more than one-third of gastroenteritis hospitalizations at the sentinel site hospitals. The predominant genotype observed was G1P[8]. Although a rotavirus surveillance network has been established, findings suggest the need to strengthen the network in the country and to continue monitoring prevalent rotavirus strains to help identify the possible emergence of new strains.
随着新的和现有的轮状病毒疫苗的出现，需要可靠和可信的数据来了解轮状病毒相关疾病的负担，以便能够就引入轮状病毒疫苗做出基于证据的决策。菲律宾的国家轮状病毒监测计划是一种基于哨点的监测，于 2012 年建立，目的是确定五岁以下患有急性肠胃炎的儿童中实验室确诊的轮状病毒病例的比例，并描述该国轮状病毒的地理分布和分子流行病学。在 2013 年至 2015 年期间，轮状病毒感染是导致五岁以下儿童患急性肠胃炎的原因，这些儿童在医院住院或在急诊室接受评估，占哨点医院肠胃炎住院的三分之一以上。观察到的主要基因型是 G1P[8]。尽管已经建立了轮状病毒监测网络，但研究结果表明，该国需要加强该网络，并继续监测流行的轮状病毒株，以帮助确定是否可能出现新的病毒株。
