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印度患者冠状动脉钙化与冠状动脉阻塞性疾病的关联。

Association of coronary calcification with obstructive disease in coronary arteries in Indian patients.

作者信息

Wasir H S, Dev V, Kaul U, Rajani M, Mukherjee S, Sharma S, Bhatia M L

机构信息

Cardiothoracic Centre, All India Institute of Medical Sciences, New Delhi.

出版信息

Clin Cardiol. 1988 Jul;11(7):461-5. doi: 10.1002/clc.4960110705.

DOI:10.1002/clc.4960110705
PMID:3046790
Abstract

A total of 1150 consecutive patients (1052 males and 98 females; age 51.2 +/- 10.1 years) with suspected coronary artery disease (Group I) were subjected to fluoroscopy for detection of coronary artery calcification (CAC) and coronary angiography. Another group (Group II) of 120 patients (95 males and 25 females; age 51.4 +/- 9.4 years) catheterized for cardiac diseases other than coronary artery disease (CAD) were subjected to the same protocol of fluoroscopy and coronary angiography to exclude incidental CAD in view of their age. CAC was present in 240 patients (20.0%) in Group I. Of these, 200 (83.4%) had triple-vessel disease (TVD); 20 (8.3%) had double-vessel disease (DVD); 19 (7.9%) had single-vessel disease (SVD); and 37 (15.4%) patients had left main coronary disease (LMCAD). Only one of these patients had insignificant CAD considered as "normal" coronary arteries (NC). Incidence of LMCAD, TVD, DVD, SVD, and NC in patients without CAC was 4.4%, 56.3%, 18.2%, 14.0%, and 11.5%, respectively. Incidence of CAC in patients with LMCAD, TVD, DVD, SVD, and NC was 48.1%, 28.1%, 10.8%, 13.0%, and 1.0% respectively. In Group II (n = 120), 24 patients (20%) had CAD, CAC was present in 5 patients with CAD (20.9%), and in two patients without CAD (2%). CAC is relatively uncommon in Indian CAD patients. Its presence, however, indicates severe multivessel disease.

摘要

共有1150例连续的疑似冠心病患者(I组,1052例男性和98例女性;年龄51.2±10.1岁)接受了荧光透视检查以检测冠状动脉钙化(CAC)并进行冠状动脉造影。另一组(II组)120例患者(95例男性和25例女性;年龄51.4±9.4岁)因非冠状动脉疾病(CAD)接受心脏导管插入术,鉴于其年龄,他们也接受了相同的荧光透视检查和冠状动脉造影方案以排除偶然的CAD。I组中有240例患者(20.0%)存在CAC。其中,200例(83.4%)患有三支血管病变(TVD);20例(8.3%)患有双支血管病变(DVD);19例(7.9%)患有单支血管病变(SVD);37例(15.4%)患者患有左主干冠状动脉疾病(LMCAD)。这些患者中只有1例患有被视为“正常”冠状动脉(NC)的轻度CAD。无CAC患者中LMCAD、TVD、DVD、SVD和NC的发生率分别为4.4%、56.3%、18.2%、14.0%和11.5%。LMCAD、TVD、DVD、SVD和NC患者中CAC的发生率分别为48.1%、28.1%、10.8%、13.0%和1.0%。在II组(n = 120)中,24例患者(20%)患有CAD,5例CAD患者(20.9%)存在CAC,2例无CAD患者(2%)存在CAC。CAC在印度CAD患者中相对不常见。然而,其存在表明存在严重的多支血管病变。

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