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对于未生育过的女性,在阴道助产术中行会阴切开术以预防产科肛门括约肌损伤是否值得?

Is episiotomy worthwile to prevent obstetric anal sphincter injury during operative vaginal delivery in nulliparous women?

作者信息

Boujenah J, Tigaizin A, Fermaut M, Murtada R, Benbara A, Benchimol M, Pharisien I, Carbillon L

机构信息

Pôle femme et enfant, groupe hospitalier universitaire Paris Seine Saint-Denis, site Jean-Verdier, avenue du 14 Juillet, 93140 Bondy, France; Université Paris 13, Sorbonne Paris cité, UFR SMBH, 93000, Bobigny, France.

Pôle femme et enfant, groupe hospitalier universitaire Paris Seine Saint-Denis, site Jean-Verdier, avenue du 14 Juillet, 93140 Bondy, France.

出版信息

Eur J Obstet Gynecol Reprod Biol. 2019 Jan;232:60-64. doi: 10.1016/j.ejogrb.2018.11.014. Epub 2018 Nov 14.

Abstract

OBJECTIVES

Episiotomy is a marker of Obstetric Anal Sphincter Injury (OASIS) condition, therefore, unmeasured factors could have biased the strength of the association between episiotomy and reduced OASIS during Operative Vaginal Delivery (OVD). The aim of this study was to compare the OASIS rate during OVD according to episiotomy practice.

STUDY DESIGN

Retrospective cohort study of all nulliparous pregnant women attempting an OVD between 2014-2017. To avoid unmeasured bias, all maternal and delivery data were prospectively captured after the birth. The strong relationship between parity and episiotomy practice (indication bias) lead to analyze only nulliparous women. Association between mediolateral episiotomy and OASIS following OVD was performing by using multivariate logistic regression analysis including significant variable in univariate analysis and relevant factors known to be associated both with OASIS and/or OVD.

RESULTS

Over the study period, 1709 (17.1%) women had an OVD, among them 40 (2.3%) had OASIS. In the 1342 (78.5%) nulliparous women, OASIS rate were 2% and 5.1% with and without episiotomy (p < 0.01). In multivariate analysis a lower incidence of OASIS with the use of episiotomy (OR 0.267 IC 0.132-0.541) were observed. The persistent occiput posterior position was associated with an increase risk of OASIS (OR 6.742 IC 2.376-19.124). Spatula/forceps, as compared to vacuum operative vaginal delivery increased the risk OASIS (OR 2.847 IC 1.311-7.168). Area under the curve of the model was 0.745.

CONCLUSION

Episiotomy is a modifiable risk factors which can contribute to reduce the risk of OASIS in nulliparous women with operative vaginal delivery. This intervention should be included in a global management of the second stage of labor.

摘要

目的

会阴切开术是产科肛门括约肌损伤(OASIS)情况的一个标志,因此,未测量的因素可能会使会阴切开术与经阴道助产分娩(OVD)期间OASIS减少之间关联的强度产生偏差。本研究的目的是根据会阴切开术的实施情况比较经阴道助产分娩期间的OASIS发生率。

研究设计

对2014年至2017年间所有尝试经阴道助产分娩的初产妇进行回顾性队列研究。为避免未测量的偏差,所有产妇和分娩数据在产后均进行前瞻性收集。经产妇与会阴切开术实施情况之间的强关联(指征偏差)导致仅分析初产妇。通过多因素逻辑回归分析来研究侧会阴切开术与经阴道助产分娩后OASIS之间的关联,该分析包括单因素分析中的显著变量以及已知与OASIS和/或经阴道助产分娩相关的相关因素。

结果

在研究期间,1709名(17.1%)妇女接受了经阴道助产分娩,其中40名(2.3%)发生了OASIS。在1342名(78.5%)初产妇中,有会阴切开术和无会阴切开术的OASIS发生率分别为2%和5.1%(p<0.01)。在多因素分析中,观察到使用会阴切开术时OASIS的发生率较低(比值比0.267,可信区间0.132 - 0.541)。持续性枕后位与OASIS风险增加相关(比值比6.742,可信区间2.376 - 19.124)。与真空经阴道助产分娩相比,使用产钳/胎头吸引器增加了OASIS的风险(比值比2.847,可信区间1.311 - 7.168)。模型的曲线下面积为0.745。

结论

会阴切开术是一个可改变的风险因素,有助于降低初产妇经阴道助产分娩时发生OASIS的风险。这种干预措施应纳入第二产程的整体管理中。

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