Röckelein G, Mischke U, Voigt H J
Pathologisches Institut, Universität Erlangen-Nürnberg.
Geburtshilfe Frauenheilkd. 1988 Jun;48(6):453-5. doi: 10.1055/s-2008-1036016.
The deposition of bile substances produces intracellular metabolic disorders in the organs so affected. Since severe cholaemia is rare in pregnancy, similar disorders of the placental cells have been not discussed up to now. We report on morphological observations in a placenta of a stillbirth in the middle of pregnancy. Bile substances are deposited in the syncytiotrophoblast and Hofbauer cells, pointing to the probable function of the Hofbauer cells as macrophages.
胆汁物质的沉积会在受影响的器官中引发细胞内代谢紊乱。由于妊娠期间严重胆汁血症较为罕见,目前尚未讨论过胎盘细胞的类似紊乱情况。我们报告了一例妊娠中期死产胎盘的形态学观察结果。胆汁物质沉积在合体滋养层细胞和霍夫鲍尔细胞中,这表明霍夫鲍尔细胞可能具有巨噬细胞的功能。