Müller Thomas J J
Institut für Organische Chemie und Makromolekulare Chemie, Heinrich-Heine-Universität Düsseldorf, Universitätsstrasse 1, D-40225 Düsseldorf, Germany.
Drug Discov Today Technol. 2018 Nov;29:19-26. doi: 10.1016/j.ddtec.2018.06.003. Epub 2018 Jul 2.
This account summarizes recent developments of aggregation-induced emissive and emission solvatochromic fluorophores by multicomponent reactions. Key intermediates are catalytically generated alkynoyl derivatives that are directly transformed into luminophores in a one-pot fashion. The conciseness in combination with ready access to tailored chromophore libraries makes this synthetic methodological concept superior over classical multistep syntheses.
本综述总结了通过多组分反应实现的聚集诱导发光和发射溶剂化变色荧光团的最新进展。关键中间体是通过催化生成的炔酰基衍生物,它们以一锅法直接转化为发光体。这种简洁性与易于获得定制的发色团库相结合,使得这种合成方法概念优于传统的多步合成。