Bellini M J, Peel R N, Terry R M
ENT Department, Seacroft Hospital, Leeds.
J Laryngol Otol. 1988 Aug;102(8):673-6. doi: 10.1017/s0022215100106127.
Since Chlamydia trachomatis was isolated from middle ear effusions of neonates with natally acquired chlamydial infection (Tipple et al., 1979), there have been several studies to detect chlamydia in older children with chronic secretory otitis media, mainly by tissue culture. In this study, the aspirates of 106 middle ear effusions of 60 children with chronic secretory otitis media were investigated for the presence of C. trachomatis, other bacteria and viruses. An amplified enzyme-linked immunoassay was used to detect the presence of chlamydia. The bacteriological and virological results mirrored previous studies in the United Kingdom and no chlamydia were found. Chlamydia do not appear to be related to the aetiology of this disease in the population examined.
自从从患有经产道获得性衣原体感染的新生儿中耳积液中分离出沙眼衣原体(蒂普尔等人,1979年)以来,已经有多项研究主要通过组织培养来检测患有慢性分泌性中耳炎的大龄儿童中的衣原体。在本研究中,对60名患有慢性分泌性中耳炎儿童的106份中耳积液抽吸物进行了检测,以确定是否存在沙眼衣原体、其他细菌和病毒。采用一种扩增酶联免疫测定法来检测衣原体的存在。细菌学和病毒学结果与英国此前的研究相似,未发现衣原体。在所研究的人群中,衣原体似乎与这种疾病的病因无关。