Lee Anselm Chi-Wai
Children's Haematology and Cancer Centre, Mount Elizabeth Hospital, Singapore, Singapore.
J Pediatr Hematol Oncol. 2019 Mar;41(2):137. doi: 10.1097/MPH.0000000000001344.
Macropolycytes are tetraploid neutrophils produced during accelerated myelopoiesis. They have been reported in adults with pernicious anemia, sepsis, and after cytotoxic chemotherapy. Two pediatric cases are reported, one after granulocyte colony-stimulating factor treatment and the other following Kawasaki disease, respectively.
巨大多分叶核细胞是在加速骨髓生成过程中产生的四倍体中性粒细胞。在患有恶性贫血、败血症的成人以及细胞毒性化疗后均有相关报道。本文报告了两例儿科病例,分别为一例在接受粒细胞集落刺激因子治疗后出现,另一例在川崎病后出现。