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动态象鼻技术:慢性症状性主动脉夹层治疗的早期结果

Kinetic Elephant Trunk Technique: Early Results in Chronic Symptomatic Aortic Dissection Management.

作者信息

Sultan Sherif, Kavanagh Edel P, Veerasingam Dave, Costache Victor, Elhelali Ala, Fitzgibbon Brian, Diethrich Edward, Hynes Niamh

机构信息

Department of Vascular and Endovascular Surgery, Western Vascular Institute, University Hospital Galway, National University of Ireland Galway, Galway, Ireland; Department of Vascular Surgery and Endovascular Surgery, Galway Clinic, Doughiska, Royal College of Surgeons in Ireland Affiliated Hospitals, Galway, Ireland.

Department of Vascular and Endovascular Surgery, Western Vascular Institute, University Hospital Galway, National University of Ireland Galway, Galway, Ireland; Department of Vascular Surgery and Endovascular Surgery, Galway Clinic, Doughiska, Royal College of Surgeons in Ireland Affiliated Hospitals, Galway, Ireland.

出版信息

Ann Vasc Surg. 2019 May;57:244-252. doi: 10.1016/j.avsg.2018.08.083. Epub 2018 Nov 23.

Abstract

BACKGROUND

The aim was to expand our understanding of the dynamic evolution of the aorta throughout the dissection time course. We investigated how the disease process can be modulated to equalize lumen pressure, enhance perfusion, and stabilize the aorta along its entire length using the kinetic elephant trunk (kET) technique.

METHODS

We performed the kET on 9 patients with chronic symptomatic aortic dissection (CSAD) as a primary or secondary intervention, regardless of the chronicity of the dissection. Endovascular scissoring of the intraluminal septum is performed in the infradiaphragmatic dissected aorta to equalize pressure between true and false lumens and allow all branched vessels to be supplied from one lumen. The Streamliner Multilayer Flow Modulator (SMFM), an uncovered cobalt-alloy aortic device, is deployed from the aortic sinus, covering the supra-aortic branches, distally into the distal aorta (primary intervention). In the case of a previous ascending aorta Dacron graft, the SMFM is deployed (secondary intervention) at the level of the Dacron graft so that it is overlapped with the graft and landed in the distal aorta.

RESULTS

In the initial study period, all-cause and aortic-related survival were 100%, respectively; all great vessels and visceral branches were patent; and freedom of stroke, end-organ ischemia, paraplegia, and renal failure were 100%.

CONCLUSIONS

The kET is a treatment process for managing CSAD. Its simplicity, consistency, and reproducibility in high-risk patients with low morbidity and mortality add to the armamentarium of the cardiovascular specialist. Further assessment of the medium- and long-term outcomes is needed to fully establish the benefits of kET.

摘要

背景

目的是加深我们对主动脉在整个夹层病程中的动态演变的理解。我们研究了如何利用动力学象鼻术(kET)来调节疾病进程,以平衡管腔压力、增强灌注并使主动脉全长保持稳定。

方法

我们对9例慢性症状性主动脉夹层(CSAD)患者进行了kET,作为主要或次要干预措施,无论夹层的慢性程度如何。在膈下夹层主动脉内进行腔内隔膜的血管内剪除以平衡真腔和假腔之间的压力,并使所有分支血管都能从一个腔获得供血。Streamliner多层血流调节器(SMFM),一种无覆盖的钴合金主动脉装置,从主动脉窦展开,覆盖主动脉弓上分支,向远端延伸至降主动脉(主要干预)。如果之前进行过升主动脉涤纶移植,则在涤纶移植水平部署SMFM(次要干预),使其与移植重叠并锚定在降主动脉。

结果

在初始研究阶段,全因生存率和主动脉相关生存率分别为100%;所有大血管和内脏分支均通畅;卒中、终末器官缺血、截瘫和肾衰竭的发生率均为0。

结论

kET是一种治疗CSAD的方法。其在高风险患者中的简单性、一致性和可重复性,且发病率和死亡率较低,为心血管专科医生增添了新的治疗手段。需要进一步评估中长期结果,以全面确定kET的益处。

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