慢性肾功能衰竭患儿的骨病：1α-羟维生素D3治疗
Bone disease in children with chronic renal failure: therapy with 1alpha-hydroxyvitamin D3.
作者信息
Postlethwaite R J, Houston I B
出版信息
Clin Endocrinol (Oxf). 1977 Dec;7 Suppl:117s-124s. doi: 10.1111/j.1365-2265.1977.tb03371.x.
Abstract
Results of 1alpha-hydroxyvitamin D3 therapy in twelve children with renal bone disease are described. Nine of the twelve children showed a good response to 0.05--0.08 microgram/kg/day. Hypercalcaemia was the only side effect and proved easy to manage because of the short half-life of 1alpha-OHD3.
摘要
本文描述了1α-羟基维生素D3治疗12例肾性骨病患儿的结果。12例患儿中有9例对0.05--0.08微克/千克/天的剂量反应良好。高钙血症是唯一的副作用，由于1α-OHD3半衰期短，所以易于处理。
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