Catauro Michelina, Tranquillo Elisabetta, Dal Poggetto Giovanni, Pasquali Mauro, Dell'Era Alessandro, Vecchio Ciprioti Stefano
Department of Engineering, University of Campania "Luigi Vanvitelli", Via Roma 29, I-81031 Aversa, Italy.
Department of Biochemistry, Biophysics and General Pathology, University of Campania "Luigi Vanvitelli", Medical School, Via L. De Crecchio 7, 80138 Naples, Italy.
Materials (Basel). 2018 Nov 24;11(12):2364. doi: 10.3390/ma11122364.
Titanium biomaterials' response has been recognized to be affected by particles size, crystal structure, and surface properties. Chemical and structural properties of these nanoparticle materials are important, but their size is the key aspect. The aim of this study is the synthesis of TiO₂ nanoparticles by the sol-gel method, which is an ideal technique to prepare nanomaterials at low temperature. The heat treatment can affect the structure of the final product and consequently its biological properties. For this reason, the chemical structure of the TiO₂ nanoparticles synthesized was investigated after each heat treatment, in order to evaluate the presence of different phases formed among the nanoparticles. FTIR spectroscopy and XRD have been used to evaluate the different structures. The results of these analyses suggest that an increase of the calcination temperature induces the formation of mixed-crystalline-phases with different content of anatase and rutile phases. The results obtained by SEM measurements suggest that an increase in the particles size accompanied by a noticeable aggregation of TiO₂ nanoparticles is due to high temperatures achieved during the thermal treatments and confirmed the presence of different content of the two crystalline phases of titanium dioxide.
钛生物材料的反应已被认为会受到颗粒大小、晶体结构和表面性质的影响。这些纳米颗粒材料的化学和结构性质很重要，但它们的尺寸是关键因素。本研究的目的是通过溶胶-凝胶法合成二氧化钛纳米颗粒，这是一种在低温下制备纳米材料的理想技术。热处理会影响最终产物的结构，进而影响其生物学性质。因此，在每次热处理后都对合成的二氧化钛纳米颗粒的化学结构进行了研究，以评估纳米颗粒中形成的不同相的存在情况。傅里叶变换红外光谱（FTIR）和X射线衍射（XRD）已被用于评估不同的结构。这些分析结果表明，煅烧温度的升高会导致形成具有不同锐钛矿相和金红石相含量的混合晶相。扫描电子显微镜（SEM）测量结果表明，颗粒尺寸的增加以及二氧化钛纳米颗粒明显的聚集是由于热处理过程中达到的高温所致，并证实了二氧化钛两种晶相的不同含量的存在。
