食管癌继发多原发癌的临床特征观察研究。
An observational study on the clinical features of esophageal cancer followed by multiple primary cancers.
机构信息
Department of Cardiovascular Surgery, Renmin hospital of Wuhan University, 238 Jiefang Road, Wuhan City of Hubei Provice, PR China.
Department of Breast & Thyroid Surgery, Renmin hospital of Wuhan University, 238 Jiefang Road, Wuhan City of Hubei Provice, PR China.
出版信息
Future Oncol. 2019 Feb;15(6):601-610. doi: 10.2217/fon-2018-0621. Epub 2018 Nov 27.
AIM
To investigate the nature of multiple primary cancers initiated by esophageal cancer-multiple primary cancers (EC-MPC).
PATIENTS & METHODS: SEER data about patients'/tumor characteristics, and survival were analyzed and compared.
RESULTS & CONCLUSION: 1727 of 29,733 registered EC patients have EC-MPC. Individuals diagnosed at 60-79 years old, earlier stage and/or moderately differentiated EC were more likely to get EC-MPC. Fewer patients in the EC-MPC group suffered from metastases. Patients in the EC-MPC group showed a longer survival rate and lower EC-specific deaths. Other factors like age, sex, race, tumor differentiation and Tumor, Node, Metastasis stage also affected survival. Radiation can improve survival. EC-MPC patients have some distinct features compared with solitary EC.
目的
探讨食管癌多发癌（EC-MPC）的性质。
患者与方法
分析并比较 SEER 数据中有关患者/肿瘤特征和生存情况的数据。
结果与结论
29733 例登记的食管癌患者中有 1727 例患有食管癌多发癌。60-79 岁、早期和/或中度分化的食管癌患者更容易患有食管癌多发癌。多发癌组的转移患者较少。多发癌组的患者生存率更高，食管癌特异性死亡人数更少。年龄、性别、种族、肿瘤分化程度和肿瘤淋巴结转移分期等其他因素也影响生存。放疗可以改善生存。与单发食管癌相比，食管癌多发癌患者有一些明显的特征。
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