Roschlau G
Pathologisches Institut, Städtischen Krankenhauses im Friedrichshain, Berlin, DDR.
Zentralbl Allg Pathol. 1988;134(2):153-8.
Drug-induced liver lesions are on a steadily rising trend and raise diagnostic problem which make for a challenge to liver biopsy interpretation. History, nomenclature, and present status of this branch of hepatology are briefly discussed. The main part is devoted to problems of histological diagnosis and typing of virus hepatitis, such as drug-induced hepatitis, the clinical data necessary for judgement of these cases and the two types of drug-related idiosyncrasy so far known.
药物性肝损伤呈稳步上升趋势，引发了诊断难题，给肝活检解读带来挑战。本文简要讨论了肝病学这一分支的历史、命名法及现状。主要部分着重探讨了病毒性肝炎的组织学诊断和分型问题，如药物性肝炎、判断这些病例所需的临床数据以及目前已知的两种药物相关特异反应。
