[Liver changes caused by drugs--a challenge for puncture biopsy pathology].

Drug-induced liver lesions are on a steadily rising trend and raise diagnostic problem which make for a challenge to liver biopsy interpretation. History, nomenclature, and present status of this branch of hepatology are briefly discussed. The main part is devoted to problems of histological diagnosis and typing of virus hepatitis, such as drug-induced hepatitis, the clinical data necessary for judgement of these cases and the two types of drug-related idiosyncrasy so far known.