单辛脂相关性肺水肿
Monooctanoin-associated pulmonary edema.
作者信息
Hine L K, Arrowsmith J B, Gallo-Torres H E
机构信息
Division of Epidemiology and Surveillance, Food and Drug Administration, Rockville, Maryland.
出版信息
Am J Gastroenterol. 1988 Oct;83(10):1128-31.
Monooctanoin is a cholesterol solvent indicated for dissolution of retained biliary stones. We summarize four reports--one from the U.S. Food and Drug Administration's Spontaneous Reporting System for Adverse Drug Reactions and three from published medical literature--of noncardiogenic pulmonary edema during intrabiliary monooctanoin in the United States. Based on these data, we show that pulmonary edema during intrabiliary monooctanoin infusion may occur in approximately one per 1000 patients treated.
单辛脂是一种胆固醇溶剂，用于溶解残留的胆结石。我们总结了四份报告——一份来自美国食品药品监督管理局的药品不良反应自发报告系统，三份来自已发表的医学文献——关于美国在胆管内注入单辛脂期间发生的非心源性肺水肿。基于这些数据，我们表明，在接受胆管内注入单辛脂治疗的患者中，大约每1000人可能会发生一例肺水肿。
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