Teng Chaolin, Cheng Yao, Wang Chao, Ren Yijing, Xu Weiyong, Xu Jin
1The Key Laboratory of Biomedical Information Engineering of Ministry of Education, Institute of Biomedical Engineering, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, 710049 Shaanxi Province People's Republic of China.
2Beijing University of Posts and Telecommunications, Beijing, China.
Cogn Neurodyn. 2018 Dec;12(6):561-568. doi: 10.1007/s11571-018-9500-6. Epub 2018 Sep 8.
Differences of EEG synchronization between normal old and young people during a working memory (WM) task were investigated. The synchronization likelihood (SL) is a novel method to assessed synchronization in multivariate time series for non-stationary systems. To evaluate this method to study the mechanisms of WM, we calculated the SL values in brain electrical activity for both resting state and task state. EEG signals were recorded from 14 young adults and 12 old adults during two different states, respectively. SL was used to measure EEG synchronization between 19 electrodes in delta, theta, alpha1, alpha2 and beta frequency bands. Bad task performance and significantly decreased EEG synchronization were found in old group compared to young group in alpha1, alpha2 and beta frequency bands during the WM task. Moreover, significantly decreased EEG synchronization in beta band in the elder was also detected during the resting state. The findings suggested that reduced EEG synchronization may be one of causes for WM capacity decline along with healthy aging.
研究了正常老年人和年轻人在工作记忆（WM）任务期间脑电图同步的差异。同步似然性（SL）是一种评估非平稳系统多变量时间序列同步性的新方法。为了评估该方法以研究工作记忆的机制，我们计算了静息状态和任务状态下脑电活动的SL值。分别在两种不同状态下记录了14名年轻成年人和12名老年人的脑电图信号。SL用于测量19个电极在δ、θ、α1、α2和β频段的脑电图同步性。在WM任务期间，与年轻组相比，老年组在α1、α2和β频段出现任务表现不佳且脑电图同步性显著降低。此外，在静息状态下也检测到老年人β频段脑电图同步性显著降低。研究结果表明，脑电图同步性降低可能是随着健康衰老工作记忆能力下降的原因之一。
