Department of Physical Medicine and Rehabilitation, Inje University Haeundae Paik Hospital, Inje University College of Medicine, , 1485 Busan, South Korea.
J Rehabil Med. 2019 Feb 1;51(2):89-96. doi: 10.2340/16501977-2509.
To critically appraise published clinical practice guidelines (CPGs) for brain tumours, and to synthesize evidence-based recommendations from a rehabilitation perspective.
A comprehensive literature search included: health science databases, CPG clearinghouse/developer websites, and grey literature up to March 2018. All brain tumour CPGs that reported systematic methods for evidence search, and clearly defined recommendations supporting evidence for rehabilitation interventions were included. Three authors independently selected potential CPGs and assessed their methodological quality using the Appraisal of Guidelines, Research and Evaluation (AGREE-II) Instrument. Recommendations from included CPGs were categorized from a rehabilitation perspective.
Of the 11 CPGs identified, only 2, developed by the National Institute for Health and Clinical Excellence (NICE) and the Australian Cancer Network (ACN), included rehabilitation components for the management of brain tumours. Both CPGs were of moderate quality. The recommendations reported were generic, and only the ACN guidelines provided detailed recommendations for rehabilitation interventions. Both guidelines recommend a comprehensive multi-disciplinary care approach. Detailed comparison, however, was not possible due to inconsistent recommendations, making it difficult to summarize rehabilitative care.
Despite rehabilitation being an integral component of the management of brain tumours, only a limited number of CPGs have incorporated recommendations for specific rehabilitation interventions. In order to improve clinical outcomes in this population future CPGs should incorporate rehabilitation interventions.
批判性评价已发表的脑肿瘤临床实践指南(CPG),并从康复角度综合基于证据的推荐意见。
全面的文献检索包括:健康科学数据库、CPG 信息中心/开发者网站以及截至 2018 年 3 月的灰色文献。所有报告系统的证据搜索方法并明确界定支持康复干预证据的脑肿瘤 CPG 均被纳入。三位作者独立选择潜在的 CPG,并使用评估指南、研究和评估(AGREE-II)工具评估其方法学质量。从康复角度对纳入 CPG 的建议进行分类。
在所确定的 11 项 CPG 中,只有由国家卫生与临床优化研究所(NICE)和澳大利亚癌症网络(ACN)制定的 2 项 CPG 包含脑肿瘤管理的康复内容。这两项 CPG 的质量均为中等。报告的建议是一般性的,只有 ACN 指南为康复干预提供了详细的建议。这两项指南都建议采用全面的多学科护理方法。然而,由于建议不一致,难以总结康复护理,因此无法进行详细比较。
尽管康复是脑肿瘤管理的一个组成部分,但只有少数 CPG 纳入了针对特定康复干预的建议。为了改善该人群的临床结局,未来的 CPG 应纳入康复干预措施。