MacDonald David, Lim Sean
Division of Oral and Maxillofacial Radiology, Faculty of Dentistry, UBC, 2199 Wesbrook Mall, Vancouver, BC, V6T 1Z3, Canada.
Oral Radiol. 2018 May;34(2):185. doi: 10.1007/s11282-018-0312-5.
Extranodal lymphomas affecting the head and neck infrequently arise within the jaw bones. Although clinical examination and conventional radiography may initially suffice for such lesions arising within the mandible, those arising within the maxillary alveolus generally require cross-sectional imaging because of the complex anatomy of this region. This study was performed to determine the prevalence, demographic characteristics, and clinical presentations of these lesions and the imaging modalities used for their diagnosis.
A systematic review (SR) on case series and another SR on case reports were performed to investigate the demographic, clinical, and radiological features of extranodal lymphomas arising within the maxillary alveolus.
Most case series were derived from just four nations, whereas the case reports were derived from a wider range of ethnicities. The more detailed case reports significantly reported at least one imaging modality. Most patients were aware of their lesions for nearly 2 months before presentation. The most frequent symptom was swelling. Most case reports included a provisional diagnosis, the most frequent of which was dental infection followed by squamous cell carcinoma.
Extranodal lymphomas arising within the maxillary alveolus were sufficiently frequent in four communities to be reported in two or more case series, and the occasional single case report indicated that such lesions are more widespread globally. Although the SR on case series revealed differences in the relative period prevalence and maxillary/mandibular ratio, the SR on case reports revealed details of the clinical presentation and imaging modalities used.
累及头颈部的结外淋巴瘤很少发生于颌骨内。虽然临床检查和传统放射摄影对下颌骨内出现的此类病变最初可能就足够了,但由于该区域解剖结构复杂,上颌牙槽内出现的病变通常需要横断面成像。本研究旨在确定这些病变的患病率、人口统计学特征、临床表现以及用于其诊断的成像方式。
对病例系列进行系统评价(SR),并对病例报告进行另一项SR,以研究上颌牙槽内结外淋巴瘤的人口统计学、临床和放射学特征。
大多数病例系列仅来自四个国家,而病例报告来自更广泛的种族。更详细的病例报告显著报告了至少一种成像方式。大多数患者在就诊前近2个月就意识到自己有病变。最常见的症状是肿胀。大多数病例报告包括初步诊断,最常见的是牙齿感染,其次是鳞状细胞癌。
上颌牙槽内出现的结外淋巴瘤在四个社区中频繁出现,足以在两个或更多病例系列中报告,偶尔的单例报告表明此类病变在全球更为普遍。虽然病例系列的SR揭示了相对期间患病率和上颌/下颌比例的差异,但病例报告的SR揭示了临床表现和使用的成像方式的细节。