Filipecka Katarzyna, Budaj Mariusz, Miśkowiak Bogdan, Mandecka Sylwia, Mandecki Radosław, Makowska-Janusik Małgorzata, Filipecki Jacek
Institute of Physics, Faculty of Mathematics and Natural Sciences, Jan Dlugosz University in Czestochowa, Poland.
Department of Optometry and Biology of Visual System, Poznan University of Medical Sciences, Poland.
Polim Med. 2018 Jan-Jun;48(1):11-16. doi: 10.17219/pim/96288.
The effects of external factors such as X-ray irradiation on the structure and physical properties of contact lenses are very important for both the patients using contact lenses and medical personnel.
The aim of the study was to investigate the effect of X-rays on the structure of Narafilcon A silicone-hydrogel contact lenses.
In order to study the structural changes caused by X-rays in Narafilcon A polymer contact lenses, the following spectroscopy methods were used: positron annihilation lifetime spectroscopy (PALS), Fourier transform middle infrared spectroscopy (FTIR) and Raman spectroscopy (RS). Irradiation of the investigated sample was carried out using an Elekta Synergy accelerator. The contact lenses were irradiated with the following total doses of X-rays: 0.05 Gy, 0.5 Gy, 0.8 Gy, and 1.0 Gy.
The PALS measurements showed that X-ray irradiation caused slight changes in the size of the free volume and the fractional free volume in the structure of the polymer contact lenses examined. However, the FTIR and RS measurements showed that X-rays did not break the monomer bonds in the polymeric structure of the sample.
The changes revealed by the PALS method may be related to possible displacement of monomer chains, resulting in changes in the dimensions and numbers of free volumes. The finding that X-ray radiation does not affect or damage polymer bonds can in the future contribute to the use of X-ray and gamma radiation to sterilize contact lenses.
X射线照射等外部因素对隐形眼镜结构和物理性质的影响，对隐形眼镜使用者和医护人员都非常重要。
本研究旨在探究X射线对纳拉非康A硅水凝胶隐形眼镜结构的影响。
为研究X射线在纳拉非康A聚合物隐形眼镜中引起的结构变化，采用了以下光谱学方法：正电子湮没寿命谱（PALS）、傅里叶变换中红外光谱（FTIR）和拉曼光谱（RS）。使用医科达Synergy加速器对研究样本进行照射。隐形眼镜接受以下总剂量的X射线照射：0.05 Gy、0.5 Gy、0.8 Gy和1.0 Gy。
PALS测量表明，X射线照射使所检测的聚合物隐形眼镜结构中的自由体积大小和自由体积分数发生了轻微变化。然而，FTIR和RS测量表明，X射线并未破坏样本聚合物结构中的单体键。
PALS方法揭示的变化可能与单体链的可能位移有关，从而导致自由体积的尺寸和数量发生变化。X射线辐射不会影响或破坏聚合物键这一发现，未来可能有助于利用X射线和γ射线对隐形眼镜进行消毒。
