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[通过换用氟西汀来停用文拉法辛]

[Discontinuing venlafaxine by switching to fluoxetine].

作者信息

Bet P M, Köktaş I O, Bergh M

出版信息

Tijdschr Psychiatr. 2018;60(11):782-785.

PMID:30484571
Abstract

Patients wanting to discontinue their antidepressant use may experience antidepressant discontinuation syndrome (ADS). This is characterized by symptoms such as nausea, vomiting, diarrhea, headaches and sweating. Withdrawal symptoms can discourage patients from permanently discontinuing antidepressants. We present the case of a 48-year-old visually impaired woman where, after a first attempt failed, venlafaxine was successfully discontinued after a switch to fluoxetine. Fluoxetine mediated discontinuation is a simple, effective and inexpensive method for patients who suffer from withdrawal symptoms when tapering off antidepressants.

摘要

想要停用抗抑郁药物的患者可能会经历抗抑郁药停药综合征(ADS)。其特征为恶心、呕吐、腹泻、头痛和出汗等症状。停药症状可能会阻碍患者永久停用抗抑郁药。我们报告一例48岁视力受损女性的病例,在首次尝试停药失败后,换用氟西汀后成功停用了文拉法辛。对于在逐渐停用抗抑郁药时出现戒断症状的患者,氟西汀介导的停药是一种简单、有效且廉价的方法。

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[Discontinuing venlafaxine by switching to fluoxetine].[通过换用氟西汀来停用文拉法辛]
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引用本文的文献

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Barriers to Safely Discontinuing Duloxetine: An Urgent Call to Action.安全停用度洛西汀的障碍:紧急行动呼吁
CNS Drugs. 2025 Jul 19. doi: 10.1007/s40263-025-01208-1.
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Fluoxetine substitution for deprescribing antidepressants: a technical approach.用氟西汀替代减停抗抑郁药:一种技术方法。
J Psychiatry Neurosci. 2025 Jul 3;50(4):E202-E209. doi: 10.1503/jpn.250054. Print 2025 Jul-Aug.