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在非洲选择选择性激光小梁成形术的理由。

The Rationale for Selective Laser Trabeculoplasty in Africa.

机构信息

West Virginia University Eye Institute, Morgantown, WV.

Department of Ophthalmology, College of Medicine, University of Ibadan, Nigeria.

出版信息

Asia Pac J Ophthalmol (Phila). 2018 Nov-Dec;7(6):387-393. doi: 10.22608/APO.2018271. Epub 2018 Nov 28.

Abstract

Glaucoma is the leading cause of irreversible blindness in Africa. The condition is treatable but not curable. There are numerous obstacles to glaucoma care in Africa, including availability, accessibility and affordability of treatments, as well as medication nonadherence among patients. Medical therapy is costly relative to the average income in Africa and it requires daily self-dosing by patients. Surgery is of limited availability in many regions in Africa, and a high proportion of patients refuse surgery because it is expensive. Selective laser trabeculoplasty (SLT) proves to be a favorable alternative to medical or surgical care, as it is highly effective and safe in people of African descent, more cost-effective than medical therapy, quick and easy to perform, and portable. The procedure also requires no postoperative care, thus obviates the issue of nonadherence. In uncontrolled studies, SLT has a high response rate and it lowers intraocular pressure by 30% to 40%, which exceeds the goal in international guidelines for initial therapies. The African Glaucoma Consortium (AGC), a member-driven stakeholder collective, has been formed in part to develop the infrastructure for continent-wide improvements in glaucoma care. It embraces SLT as a potential key tool in their development plans. The mission of AGC includes improving clinical care by educating existing and new health care professionals to expand the provider network, by conducting trials to identify optimal care strategies for glaucoma in Africa, and by facilitating the development of an integrated network of Centers of Excellence to bring SLT and other crucial glaucoma therapies to communities throughout Africa.

摘要

青光眼是非洲导致不可逆性失明的主要原因。这种疾病可以治疗,但无法治愈。非洲的青光眼治疗存在许多障碍,包括治疗方法的可及性、可及性和可负担性,以及患者的药物不依从性。与非洲的平均收入相比,药物治疗费用昂贵,而且需要患者每天自行服药。在非洲的许多地区,手术的可及性有限,而且由于手术费用昂贵,很大一部分患者拒绝手术。选择性激光小梁成形术 (SLT) 被证明是一种优于药物或手术治疗的方法,因为它在非洲裔人群中非常有效且安全,比药物治疗更具成本效益,快速简便,便于携带。该手术还不需要术后护理,因此避免了药物不依从的问题。在未受控制的研究中,SLT 的反应率很高,可将眼压降低 30%至 40%,超过国际指南中初始治疗的目标。非洲青光眼联合会 (AGC) 是一个由利益相关者驱动的成员集体,其部分目的是为非洲大陆改善青光眼治疗建立基础设施。它将 SLT 视为其发展计划中的潜在关键工具。AGC 的使命包括通过教育现有和新的医疗保健专业人员来扩大服务提供者网络,通过开展试验来确定非洲青光眼的最佳护理策略,以及通过促进卓越中心的综合网络的发展,将 SLT 和其他重要的青光眼治疗方法带到整个非洲的社区,从而改善临床护理。

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