Qin Ya-Fei, Li Na, Shi Yong-Xin, Sun Kai, Li Zhi-Jun, Li Hui
Department of Orthopedics, Tianjin Medical University General Hospital, Tianjin 300052, PR China.
Tianjin Medical University General Hospital, Tianjin, 300052, PR China.
J Comp Eff Res. 2018 Dec;7(12):1181-1193. doi: 10.2217/cer-2018-0064. Epub 2018 Nov 28.
A meta-analysis concentrated on the effect of intramedullary and extramedullary systems on total knee arthroplasty.
Potential academic articles were identified from Cochrane Library, Medline, PubMed, Embase, ScienceDirect, CNKI, WanFang, VIP and other databases. The STATA version was used to analyze the pooled data.
There are obvious significant differences in drainage volume and transfusion rate. There was no significant difference in lower limb coronal alignment, coronal and sagittal alignment of the femoral component, operation time, postoperative knee score and complications.
Our meta-analysis shows that the alignment of the extramedullary distal femur osteotomy is as accurate as intramedullary systems. Furthermore, extramedullary distal femur osteotomy without invading the femoral medullary cavity could reduce postoperative bleeding and the transfusion rate. Furthermore, research is required to test the robustness of our findings when more data is available and by undertaking both Bayesian and frequentist methods. When more data are available, the heterogeneity can be further explored through sensitivity analysis, and the available data can be combined to verify the hypothesis.
进行一项荟萃分析,聚焦髓内和髓外系统对全膝关节置换术的影响。
从Cochrane图书馆、Medline、PubMed、Embase、ScienceDirect、中国知网、万方、维普等数据库中检索潜在的学术文章。使用STATA软件版本分析汇总数据。
在引流量和输血率方面存在明显显著差异。在下肢冠状位对线、股骨组件的冠状位和矢状位对线、手术时间、术后膝关节评分及并发症方面无显著差异。
我们的荟萃分析表明,髓外股骨远端截骨的对线与髓内系统一样准确。此外,不侵入股骨髓腔的髓外股骨远端截骨可减少术后出血和输血率。此外,当有更多数据可用时,需要通过贝叶斯和频率论方法来检验我们研究结果的稳健性。当有更多数据可用时,可通过敏感性分析进一步探讨异质性,并合并现有数据以验证假设。