Aji Arif Sabta, Yerizel Eti, Lipoeto Nur Indrawaty
Department of Biomedical Science, Faculty of Medicine, University of Andalas, Padang, Indonesia.
Department of Biochemistry, Faculty of Medicine, University of Andalas, Padang, Indonesia.
Asia Pac J Clin Nutr. 2018;27(6):1286-1293. doi: 10.6133/apjcn.201811_27(6).0016.
An adequate level of maternal vitamin D is essential for maternal and fetal health during pregnancy. We examined the relationship between lifestyle, maternal vitamin D intake and the vitamin D status of pregnant women. Methods and Study designs: The sample of the cross-sectional study was 203 third trimester pregnant women in September-November 2016 in four different districts of West Sumatra, Indonesia. Questionnaire was used to assess lifestyles, dietary intake, anthropometry, maternal characteristics, demography and socioeconomic data. The Vitamin D serum level was measured by the ELISA method and the data were analyzed using descriptive statistics, chi-squared tests, Pearson's correlation and logistic regression.
160 blood serum samples of pregnant women were collected. The means of 25-hydroxyvitamin D and maternal vitamin D intake were 29.06±11.39 ng/mL and 7.92±5.26 μg/day respectively. The prevalence of vitamin D deficiency- insufficiency was 61.25%, and more than 85% of the women had inadequate vitamin D intake. We found that living in mountainous areas (p=0.03) and low physical activity (p=0.02) were significantly associated with maternal vitamin D levels as a prediction factor. In addition, younger who had lower pre-pregnancy weight had a higher prevalence of vitamin D deficiency.
Low levels of vitamin D were common among pregnant women in West Sumatra, Indonesia. Additional intake of vitamin D from supplements may be important to meet the recommended dietary level for pregnant women.
孕期母体充足的维生素D水平对母婴健康至关重要。我们研究了生活方式、母体维生素D摄入量与孕妇维生素D状况之间的关系。
该横断面研究的样本为2016年9月至11月印度尼西亚西苏门答腊四个不同地区的203名孕晚期妇女。采用问卷调查评估生活方式、饮食摄入、人体测量学、母体特征、人口统计学和社会经济数据。采用ELISA法测定血清维生素D水平,并使用描述性统计、卡方检验、Pearson相关性分析和逻辑回归分析数据。
收集了160份孕妇血清样本。25-羟维生素D和母体维生素D摄入量的平均值分别为29.06±11.39 ng/mL和7.92±5.26 μg/天。维生素D缺乏-不足的患病率为61.25%,超过85%的妇女维生素D摄入量不足。我们发现,居住在山区(p=0.03)和低体力活动(p=0.02)作为预测因素与母体维生素D水平显著相关。此外,孕前体重较低的年轻孕妇维生素D缺乏的患病率较高。
在印度尼西亚西苏门答腊,孕妇中维生素D水平较低很常见。从补充剂中额外摄入维生素D对于达到孕妇推荐膳食水平可能很重要。