Shakerian B, Razavi N, Mandegar M H
Department of Cardiovascular Surgery, Tehran University of Medical Sciences, Tehran, Iran.
Department of Genetics, Shahrekord Azad University, Shahrekord, Iran.
Int J Organ Transplant Med. 2018;9(3):140-143. Epub 2018 Aug 1.
The incidence of invasive fungal infections is lower than that of bacterial infections in heart transplant recipients. However, they are always life-threatening. Clinical manifestations may range from asymptomatic colonization to disseminated infection. This complication is responsible for significant morbidity and mortality, particularly in heart transplant recipients. Herein, we present on a cardiac transplant recipient who presented with invasive pulmonary aspergillosis quickly leading to death, in spite of early diagnosis and aggressive therapy. It just took 10 hours from the diagnosis to death. In other reports, this period was at least 12 days.
心脏移植受者侵袭性真菌感染的发生率低于细菌感染。然而，它们始终危及生命。临床表现可能从无症状定植到播散性感染。这种并发症会导致显著的发病率和死亡率，尤其是在心脏移植受者中。在此，我们报告一例心脏移植受者，尽管早期诊断并积极治疗，但仍迅速出现侵袭性肺曲霉病并导致死亡。从诊断到死亡仅用了10小时。在其他报告中，这段时间至少为12天。
