Peng Guangge, Zhang Jingyu, Jia Baixue, Xu Ziqi, Mo Dapeng, Ma Ning, Gao Feng, Miao Zhongrong
Department of Interventional Neuroradiology, Beijing Tiantan Hospital, Capital Medical University, The No.6, Tiantan Xili, Dongcheng District, Beijing, China.
National Clinical Research Center for Neurological Diseases, Center of Stroke, Beijing Key Laboratory of Translational Medicine for Cerebrovascular Diseases, Beijing Institute for Brain Disorders, The No.6, Tiantan Xili, Dongcheng District, Beijing, China.
Neuroradiology. 2019 Jan;61(1):97-102. doi: 10.1007/s00234-018-2133-y. Epub 2018 Nov 28.
The aim of our study is to report the peri-procedural complications and long-term stroke recurrent rate of symptomatic intracranial atherosclerosis (ICAS) patients who underwent submaximal primary angioplasty.
This is a retrospective analysis of consecutive patients in a single center who underwent submaximal primary angioplasty between January 1, 2012 and December 31, 2015. The peri-procedural complications and long-term outcomes are reported.
Primary angioplasty was successfully performed in 129 patients (97.0%). The mean degree of pre-procedural stenosis was 81.9 ± 10.2%, and the degree of residual stenosis was 40.7 ± 19.1%. There were nine (6.8%) peri-procedural complications within 30 days, including seven ischemic strokes, one subarachnoid hemorrhage, and one asymptomatic intracerebral hemorrhage. None of them resulted in death. One-year follow-up was available in 122 patients (91.7%). Three more ischemic strokes (2.3%) which were in the territory of the treated artery occurred between 30 days and 1 year. The 1-year stroke and death rate was 9.0%, including peri-procedural stroke. Kaplan-Meier analysis showed a 3-year stroke-free survival of 87.2%.
Submaximal primary angioplasty can be performed with a low peri-procedural complication rate and relatively good clinical outcome at long-term follow-up for symptomatic ICAS patients.
我们研究的目的是报告接受次最大量原发性血管成形术的症状性颅内动脉粥样硬化（ICAS）患者的围手术期并发症和长期卒中复发率。
这是一项对2012年1月1日至2015年12月31日期间在单一中心接受次最大量原发性血管成形术的连续患者的回顾性分析。报告围手术期并发症和长期结局。
129例患者（97.0%）成功进行了原发性血管成形术。术前狭窄的平均程度为81.9±10.2%，残余狭窄程度为40.7±19.1%。30天内有9例（6.8%）围手术期并发症，包括7例缺血性卒中、1例蛛网膜下腔出血和1例无症状脑出血。均未导致死亡。122例患者（91.7%）进行了1年随访。在30天至1年之间又发生了3例（2.3%）治疗动脉供血区域的缺血性卒中。1年卒中及死亡率为9.0%，包括围手术期卒中。Kaplan-Meier分析显示3年无卒中生存率为87.2%。
对于症状性ICAS患者，次最大量原发性血管成形术围手术期并发症发生率低，长期随访临床结局相对较好。
