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偏头痛女性的饮食模式与偏头痛发作频率的关联。

The association of dietary patterns with migraine attack frequency in migrainous women.

作者信息

Hajjarzadeh Samaneh, Mahdavi Reza, Shalilahmadi Davood, Nikniaz Zeinab

机构信息

Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran.

Nutrition Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.

出版信息

Nutr Neurosci. 2020 Sep;23(9):724-730. doi: 10.1080/1028415X.2018.1550890. Epub 2018 Nov 29.

DOI:10.1080/1028415X.2018.1550890
PMID:30489231
Abstract

Migraine is a debilitating neurovascular disorder. The relation of diets and migraine is a controversial topic yet. This study assessed the association of dietary patterns of migrainous women with attack frequency. In this cross sectional study 285 volunteer migrainous women (25-55 years old) based on the third edition of International Classification of Headache Disorders (ICHD-3) recruited from neurology clinics of Golestan Hospital in Ahwaz, Iran. For collecting the data, the patients were interviewed. Dietary patterns of participants were assessed using a validated semi quantitative food frequency questionnaire which included 168 food items. Extraction of dietary patterns was performed using factor analysis. The association between dietary patterns and migraine attack frequency was analyzed by ordinal regression. Two major dietary patterns which were extracted include the "western" and the "healthy" patterns. After adjustment for confounders, subjects with high adherence to healthy pattern had lower attack frequency (OR: 1.09; 95% CI: [0.51-2.25]; for trend = 0.04); whereas, subjects with high adherence to western pattern had more attack frequency (OR: 0.89; 95% CI: [0.42-1.88]; for trend = 0.02) significantly. Based on the results, adherence to healthy dietary pattern in migrainous women may be effective in controlling migraine attacks.

摘要

偏头痛是一种使人衰弱的神经血管疾病。饮食与偏头痛之间的关系仍是一个有争议的话题。本研究评估了偏头痛女性的饮食模式与发作频率之间的关联。在这项横断面研究中,根据国际头痛疾病分类第三版(ICHD-3),从伊朗阿瓦士戈勒斯坦医院的神经科诊所招募了285名志愿者偏头痛女性(25至55岁)。为了收集数据,对患者进行了访谈。使用经过验证的半定量食物频率问卷评估参与者的饮食模式,该问卷包含168种食物。使用因子分析提取饮食模式。通过有序回归分析饮食模式与偏头痛发作频率之间的关联。提取出的两种主要饮食模式包括“西方”模式和“健康”模式。在对混杂因素进行调整后,高度遵循健康模式的受试者发作频率较低(OR:1.09;95%CI:[0.51 - 2.25];趋势检验P = 0.04);而高度遵循西方模式的受试者发作频率较高(OR:0.89;95%CI:[0.42 - 1.88];趋势检验P = 0.02),差异具有统计学意义。基于这些结果,偏头痛女性遵循健康饮食模式可能对控制偏头痛发作有效。

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