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急性髓系白血病中的皮肤白血病预示着预后不良。

Leukemia cutis in acute myeloid leukemia signifies a poor prognosis.

作者信息

Krooks Jolie A, Weatherall Angela G

机构信息

Charles E. Schmidt College of Medicine, Florida Atlantic University, Boca Raton, USA.

Department of Clinical Biomedical Science, Charles E. Schmidt College of Medicine, Florida Atlantic University, Boca Raton; ClearlyDerm, Boca Raton, Florida, USA.

出版信息

Cutis. 2018 Oct;102(4):266;271;272.

PMID:30489552
Abstract

Leukemia cutis (LC) is a rare neoplastic infiltration of the skin or subcutaneous tissue by leukemic cells. Because it correlates with sites of additional extramedullary involvement, it typically portends a poor prognosis. Although most cases of LC present concurrently with bone marrow infiltration, skin findings may precede systemic involvement in some cases; thus, early detection by dermatologists is essential. We report a case of a 66-year-old man who was diagnosed with acute myeloid leukemia (AML) based on the cutaneous presentation of LC.

摘要

皮肤白血病(LC)是白血病细胞对皮肤或皮下组织的罕见肿瘤浸润。由于它与其他髓外受累部位相关,通常预示预后不良。虽然大多数LC病例与骨髓浸润同时出现,但在某些情况下皮肤表现可能先于全身受累;因此,皮肤科医生的早期检测至关重要。我们报告一例66岁男性患者,其基于LC的皮肤表现被诊断为急性髓系白血病(AML)。

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