Widener H L, Littman B H
JAMA. 1978 Mar 13;239(11):1062-4.
A patient with systemic lupus erythematosus had chills, fever, and headache on four separate occasions after ibuprofen ingestion. One such episode was accompanied by cerebrospinal fluid findings compatible with meningitis. Drug rechallenge under controlled conditions established the relationship between ibuprofen ingestion and meningitis.
一名系统性红斑狼疮患者在服用布洛芬后四次出现寒战、发热和头痛。其中一次发作伴有与脑膜炎相符的脑脊液检查结果。在可控条件下进行药物激发试验确定了服用布洛芬与脑膜炎之间的关系。