Udonsi J K
Department of Zoology, Faculty of Science, University of Port Harcourt.
Folia Parasitol (Praha). 1988;35(2):147-55.
A 12-months study on bancroftian filariasis was carried out in the Igwun basin, Nigeria. A total of 1,418 individuals (768 males, and 650 females) were examined for microfilaremia and clinical filarial stigmata. There were 14.3% and 11.1% male and female point prevalence rates, respectively, and an overall prevalence of 12.8%. Prevalence rates and microfilarial density increased with age. The highest mff density of 35 mff/20 ml blood occurred in the 40-49 year old male individuals. Disease rates of 55.5 and 65.3% were recorded for males and females respectively. Chyluria (9.3% males, 16.7% females), hydrocele (17.8%), elephantiasis (15.9% males, 29.2% females), and enlarged groin glands (16.4% males, 19.4% females) were the major clinical signs, all associated with microfilaremia. Anopheles gambiae and Cules pipiens were the principal vectors. The estimated mean daily, weekly, and monthly per capita biting densities were 26, 161, and 753 respectively. The overall infection rate of mosquitoes was 22.3%, with a mean mff density of approximately 5 mff/mosquito. These vector parameters were indicative of active transmission in the area, and may be responsible for the high prevalence of infection, the diversity of clinical signs, and high morbidity rates.
在尼日利亚的伊格温盆地开展了一项为期12个月的班氏丝虫病研究。共对1418人（768名男性和650名女性）进行了微丝蚴血症和临床丝虫病体征检查。男性和女性的点患病率分别为14.3%和11.1%，总体患病率为12.8%。患病率和微丝蚴密度随年龄增长而增加。40 - 49岁男性个体的最高微丝蚴密度为每20毫升血液中有35条微丝蚴。男性和女性的发病率分别记录为55.5%和65.3%。乳糜尿（男性9.3%，女性16.7%）、鞘膜积液（17.8%）、象皮肿（男性15.9%，女性29.2%）和腹股沟淋巴结肿大（男性16.4%，女性19.4%）是主要临床体征，均与微丝蚴血症相关。冈比亚按蚊和致倦库蚊是主要传播媒介。估计平均每日、每周和每月人均叮咬密度分别为26、161和753。蚊子的总体感染率为22.3%，平均微丝蚴密度约为每只蚊子5条微丝蚴。这些媒介参数表明该地区存在活跃传播，可能是感染率高、临床体征多样和发病率高的原因。
