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原位肝移植中的肝动脉

The hepatic artery in orthotopic liver transplantation.

作者信息

Lerut J P, Gordon R D, Tzakis A G, Stieber A C, Iwatsuki S, Starzl T E

出版信息

Helv Chir Acta. 1988 Jul;55(3):367-78.

PMID:3049463
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3086426/
Abstract

Hepatic artery thrombosis (HAT) is a dreadful complication of orthotopic liver transplantation (OLT). This complication occurred in 27 grafts (68% = 27/393 grafts) in 25 patients (9% = 25/313 patients). HAT was responsible for a high mortality (64% = 16/25 patients) despite a high retransplantation rate (70% = 19/27 grafts). HAT should be suspected in case of fulminant liver failure, delayed bile leak or unexplained fever of sepsis of unknown etiology occurring after liver transplantation. Pulsed doppler examination and arteriogram are the decisive diagnostic procedures. Patients presenting HAT can only be rescued by early diagnosis and retransplantation. Aneurysms of the hepatic arterial supply must also be treated urgently, either by conventional vascular repair if possible or by retransplantation, because or the high incidence of fatal rupture (3/4 patients = 75%).

摘要

肝动脉血栓形成(HAT)是原位肝移植(OLT)的一种可怕并发症。该并发症发生在25例患者(9% = 25/313例患者)的27个移植物中(68% = 27/393个移植物)。尽管再次移植率较高(70% = 19/27个移植物),但HAT导致了高死亡率(64% = 16/25例患者)。肝移植后若出现暴发性肝衰竭、延迟性胆漏或病因不明的不明原因脓毒症发热,应怀疑有HAT。脉冲多普勒检查和动脉造影是决定性的诊断方法。出现HAT的患者只有通过早期诊断和再次移植才能获救。肝动脉供血的动脉瘤也必须紧急治疗,若可能可通过传统血管修复或再次移植,因为其致命破裂的发生率很高(3/4例患者 = 75%)。

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The hepatic artery in orthotopic liver transplantation.原位肝移植中的肝动脉
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引用本文的文献

1
Case report: Immediate revascularization for symptomatic hepatic artery pseudoaneurysm after orthotopic liver transplantation? A case series and literature review.病例报告:原位肝移植术后有症状的肝动脉假性动脉瘤的即刻血管重建?病例系列及文献综述。
Front Surg. 2023 Jun 27;10:1169556. doi: 10.3389/fsurg.2023.1169556. eCollection 2023.
2
Urgent revascularization of liver allografts after early hepatic artery thrombosis.肝移植术后早期肝动脉血栓形成后的紧急血管重建
Transplantation. 1996 Dec 15;62(11):1584-7. doi: 10.1097/00007890-199612150-00010.

本文引用的文献

1
Factors in the Development of Liver Transplantation.肝移植发展的因素
Transplant Proc. 1985 Oct;17(Suppl 2):107-119.
2
Evolution of liver transplantation.肝移植的发展历程。
Hepatology. 1982 Sep-Oct;2(5):614-36. doi: 10.1002/hep.1840020516.
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Alternative methods of arterialization of the hepatic graft.
Surg Gynecol Obstet. 1984 Nov;159(5):490-3.
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A growth factor in fine vascular anastomoses.精细血管吻合术中的一种生长因子。
Surg Gynecol Obstet. 1984 Aug;159(2):164-5.
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Clinical presentation of hepatic artery thrombosis after liver transplantation in the cyclosporine era.环孢素时代肝移植术后肝动脉血栓形成的临床表现
Transplantation. 1985 Dec;40(6):667-71. doi: 10.1097/00007890-198512000-00019.
6
A simplified technique for revascularization of homografts of the liver with a variant right hepatic artery from the superior mesenteric artery.一种用于肠系膜上动脉发出变异右肝动脉的同种异体肝移植血管重建的简化技术。
Surg Gynecol Obstet. 1985 May;160(5):474-6.
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Hepatic artery in liver transplantation.肝移植中的肝动脉
Transplant Proc. 1987 Feb;19(1 Pt 3):2406-11.
8
Biliary tract complications in human orthotopic liver transplantation.人类原位肝移植中的胆道并发症。
Transplantation. 1987 Jan;43(1):47-51. doi: 10.1097/00007890-198701000-00011.
9
Doppler ultrasound as a screen for hepatic artery thrombosis after liver transplantation.多普勒超声作为肝移植术后肝动脉血栓形成的筛查手段。
Transplantation. 1986 Apr;41(4):539-41. doi: 10.1097/00007890-198604000-00026.
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Superoxide dismutase improves organ preservation in liver transplantation.超氧化物歧化酶可改善肝移植中的器官保存。
Transplant Proc. 1988 Feb;20(1 Suppl 1):961-4.