Al-Hakim Ramsey, Schenning Ryan
Oregon Health & Science University, Charles T. Dotter Department of Interventional Radiology, Portland, OR..
Oregon Health & Science University, Charles T. Dotter Department of Interventional Radiology, Portland, OR.
Tech Vasc Interv Radiol. 2018 Sep;21(3):146-155. doi: 10.1053/j.tvir.2018.06.004. Epub 2018 Jun 14.
Thoracic endovascular aortic repair (TEVAR) is a rapidly growing and improving technique for the management of thoracic aortic aneurysms, dissections, and traumatic aortic injury. These disease processes were previously treated exclusively by surgery, but TEVAR has substantially improved patient outcomes including reduced mortality, reduced paraplegia rate, and shorter hospital and/or intensive care unit stay compared to open surgery. TEVAR was initially isolated to the descending thoracic aorta, but the advent of advanced techniques has extended the scope to well beyond the left subclavian artery and into Zone 0. Recent techniques include chimney grafts, periscope grafts, in situ fenestrations, and physician modified grafts. In addition, commercial branched aortic devices are currently on trial and will likely vastly extend the off-the-shelf capabilities of TEVAR for aortic arch disease. This paper reviews the data, concepts, and technical aspects of current advanced TEVAR techniques, as well as ongoing clinical trials for thoracic branched aortic devices.
胸主动脉腔内修复术(TEVAR)是一种在治疗胸主动脉瘤、主动脉夹层和创伤性主动脉损伤方面迅速发展且不断完善的技术。这些疾病进程以前完全通过手术治疗,但与开放手术相比,TEVAR已显著改善了患者的治疗效果,包括降低死亡率、降低截瘫发生率以及缩短住院时间和/或重症监护病房停留时间。TEVAR最初仅用于降主动脉,但先进技术的出现已将其范围扩展到远超过左锁骨下动脉并进入0区。最近的技术包括烟囱式移植物、潜望镜式移植物、原位开窗术和医生改良移植物。此外,商用分支主动脉装置目前正在进行试验,可能会极大地扩展TEVAR治疗主动脉弓疾病的现货供应能力。本文回顾了当前先进TEVAR技术的数据、概念和技术方面,以及胸部分支主动脉装置正在进行的临床试验。