Foulks G N, Austin R, Knowlton G
Duke University Eye Center, Durham, North Carolina.
J Ocul Pharmacol. 1988 Summer;4(2):111-5. doi: 10.1089/jop.1988.4.111.
Thirty-nine patients with bacterial ocular surface infections (conjunctivitis, blepharitis or blepharoconjunctivitis) were evaluated after treatment with a topically applied ophthalmic solution containing trimethoprim. A combination of trimethoprim and polymixin B (TP) produced identical clinical and microbiologic responses when compared to a solution containing, in addition to trimethoprim and polymyxin B, sulfacetamide. The sulfa component was not essential to produce desired clinical and microbiologic results.
39例细菌性眼表感染（结膜炎、睑缘炎或睑结膜炎）患者在使用含甲氧苄啶的局部应用眼科溶液治疗后接受了评估。与除甲氧苄啶和多粘菌素B外还含有磺胺醋酰的溶液相比，甲氧苄啶和多粘菌素B的组合（TP）产生了相同的临床和微生物学反应。磺胺成分对于产生理想的临床和微生物学结果并非必不可少。
