Cancer Discov. 2019 Jan;9(1):8. doi: 10.1158/2159-8290.CD-NB2018-162. Epub 2018 Nov 30.
A novel anti-HER2 therapy, ZW25, may be effective and well tolerated in patients with a variety of HER2-positive cancers. In a phase I trial, patients treated with the drug-most of whom had gastroesophageal or colorectal cancer-had an objective response rate of 41% and mild side effects.
一种新型抗HER2疗法ZW25,可能对多种HER2阳性癌症患者有效且耐受性良好。在一项I期试验中,接受该药物治疗的患者(其中大多数患有胃食管癌或结直肠癌)客观缓解率为41%,且副作用轻微。