Modi Manish, Goyal Manoj Kumar, Jain Anumiti, Sawhney Suhalika Singhal, Sharma Kusum, Vyas Sameer, Ahuja Chirag Kamal
Department of Neurology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Department of Medical Microbiology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Neurol India. 2018 Nov-Dec;66(6):1550-1571. doi: 10.4103/0028-3886.246224.
It has been approximately five decades since Dastur et al., published their seminal work on pathology of tuberculous meningitis (TBM). Though most of their findings find relevance in today's era, there is an important difference; these findings can now be replicated during life using modern day technology. In this article, we review the seminal words of Professor Dastur and colleagues, analyse their findings, interpret how these revolutionized our understanding of TBM and highlight their relevance in today's era. We also discuss challenges in the management of TBM, which we continue to face today and the various options required to overcome these challenges.
自达斯特尔等人发表关于结核性脑膜炎（TBM）病理学的开创性著作以来，大约已经过去了五十年。尽管他们的大多数发现至今仍具有相关性，但有一个重要的不同之处；现在可以利用现代技术在患者生前重现这些发现。在本文中，我们回顾了达斯特尔教授及其同事的开创性言论，分析了他们的发现，解读这些发现如何彻底改变了我们对TBM的理解，并强调了它们在当今时代的相关性。我们还讨论了TBM管理中我们至今仍面临的挑战以及克服这些挑战所需的各种选择。
