Mutagenic activities of selected nitrofluoranthene derivatives in Salmonella typhimurium strains TA98, TA98NR and TA98/1,8-DNP6.
作者信息
Zielinska B, Arey J, Harger W P, Lee R W
机构信息
Statewide Air Pollution Research Center, University of California, Riverside 92521.
出版信息
Mutat Res. 1988 Oct;206(2):131-40. doi: 10.1016/0165-1218(88)90152-8.
PMID:3050495
Abstract
The mutagenic activities of novel nitrofluoranthene derivatives in Salmonella strains TA98, TA98NR and TA98/1,8-DNP6 (with and without S9 addition) are given. These derivatives were produced from the reactions of fluoranthene (FL) and its directly mutagenic 2- and 3-nitro derivatives with covalent dinitrogen pentoxide (N2O5) in CCl4 solution at ambient temperature. The influence of the addition of a nitro group on the observed activity of the resulting di- and tri-nitrofluoranthenes is discussed.
摘要
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