鼻窦未分化癌的肿瘤学管理
Oncologic management of sinonasal undifferentiated carcinoma.
作者信息
Tyler Matthew A, Holmes Brittany, Patel Zara M
机构信息
Department of Otolaryngology-Head and Neck Surgery.
Department of Pathology, Stanford University School of Medicine, Stanford, California, USA.
出版信息
Curr Opin Otolaryngol Head Neck Surg. 2019 Feb;27(1):59-66. doi: 10.1097/MOO.0000000000000513.
PURPOSE OF REVIEW
This article reviews the latest treatment paradigms in sinonasal undifferentiated carcinoma (SNUC).
RECENT FINDINGS
The aggressive biology and associated advanced presentation of SNUC make successful treatment a challenge shared across medical specialties. Still, studies reporting outcomes in SNUC indicate that an aggressive treatment strategy consisting of surgery, radiation and chemotherapy offers the best chance of prolonged survival.
SUMMARY
Successful treatment of SNUC requires highly specialized care at tertiary cancer treatment facilities. A better understanding of the biology of the disease coupled with increasing outcome reporting will lead to optimized treatment regimens.
综述目的
本文综述了鼻窦未分化癌（SNUC）的最新治疗模式。
最新发现
SNUC具有侵袭性生物学行为及相关的晚期表现，这使得成功治疗成为各个医学专科共同面临的挑战。尽管如此，关于SNUC治疗结果的研究表明，由手术、放疗和化疗组成的积极治疗策略提供了延长生存期的最佳机会。
总结
SNUC的成功治疗需要在三级癌症治疗机构接受高度专业化的护理。对该疾病生物学特性的更好理解以及更多的结果报告将带来优化的治疗方案。
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