Brandner Sonja, Aeberhard Celine, Mueller Michael D, Kuhn Annette
Frauenzimmer Bern AG, Bern, Switzerland.
Ginekol Pol. 2018;89(11):587-592. doi: 10.5603/GP.a2018.0101.
The need for pelvic floor surgery will increase with an aging population in the future. Aim of this prospective study was to evaluate the evolution of cognitive function in elderly women after urogynaecological surgery.
Between 2010 and 2014, 51 female patients 70 years and older who underwent urogynaecological surgery participated in this study. Geriatric and urogynaecological assessment were performed before and six weeks after surgery, including the Mini-COG test, the clock-drawing test, a depression scale, an activities of daily living questionnaire, and the German pelvic floor questionnaire.
Mean age was 77 years (range 70-91). Overall, 15 women were operated for incontinence, 31 for prolapse, and five for miscellaneous reasons. Only two (3.9%) of the 51 women developed postoperative delirium. Abnormal cognitive findings increased from preoperatively 15.7% to 39.2% six weeks after surgery (odds ratio 3.4, 95% confidence interval 1.3 to 8.7, p < 0.001). There were no statistically significant pre-post differences in activities of daily living and depression scores. Pelvic floor function indices improved significantly Conclusion: This study shows an overall decline of cognitive function in a vulnerable group of elderly women during the short-term postoperative period. Postoperative cognitive dysfunction (POCD) after surgery has been described for other types of non-cardiac surgery but has been understudied in urogynaecological surgery. These patients need interdisciplinary management to prevent or minimize adverse effects of surgery on cognitive function.
随着未来人口老龄化,盆底手术的需求将会增加。本前瞻性研究的目的是评估老年女性在泌尿妇科手术后认知功能的变化。
2010年至2014年期间,51名70岁及以上接受泌尿妇科手术的女性患者参与了本研究。在手术前和术后六周进行老年医学和泌尿妇科评估,包括简易精神状态检查表测试、画钟试验、抑郁量表、日常生活活动问卷以及德国盆底问卷。
平均年龄为77岁(范围70 - 91岁)。总体而言,15名女性因尿失禁接受手术,31名因脱垂接受手术,5名因其他原因接受手术。51名女性中只有两名(3.9%)出现术后谵妄。认知异常结果从术前的15.7%增加到术后六周的39.2%(优势比3.4,95%置信区间1.3至8.7,p < 0.001)。日常生活活动和抑郁评分在术前和术后没有统计学上的显著差异。盆底功能指标显著改善。结论:本研究表明,在术后短期内,一组脆弱的老年女性的认知功能总体下降。其他类型的非心脏手术术后已出现术后认知功能障碍(POCD),但在泌尿妇科手术中对此研究较少。这些患者需要跨学科管理,以预防或尽量减少手术对认知功能的不良影响。