Channir Hani Ibrahim, Isenberg Asher Lou, Rubek Niclas, Lomholt Anne Fog, Scott Susanne Irene, Tvedskov Jesper Flitenborg, Charabi Birgitte Wittenborg, Buchwald Christian von
Ugeskr Laeger. 2018 Nov 19;180(47).
Oropharyngeal squamous cell carcinoma (OPSCC) induced by human papillomavirus (HPV) is highly prevalent in the western part of the world. Patients with HPV-induced OPSCC are often younger and have a much better prognosis than patients with HPV-negative OPSCC. The newly introduced transoral robotic surgery offers the ability to perform en bloc tumour resection with good margin control. It may be an alternative to the traditional radiation therapy for early-stage OPSCC. A Danish randomised clinical trial is now aiming at comparing these two treatments with a focus on long-term functional outcomes.
人乳头瘤病毒（HPV）引发的口咽鳞状细胞癌（OPSCC）在世界西部极为普遍。HPV引发的OPSCC患者往往更年轻，且预后比HPV阴性的OPSCC患者好得多。新引入的经口机器人手术能够进行整块肿瘤切除，并能很好地控制切缘。对于早期OPSCC，它可能是传统放疗的一种替代方案。一项丹麦随机临床试验目前旨在比较这两种治疗方法，重点关注长期功能结果。
