心房颤动中的性别差异：流行病学、管理及结局综述
Gender Differences in Atrial Fibrillation: A Review of Epidemiology, Management, and Outcomes.
作者信息
Westerman Stacy, Wenger Nanette
机构信息
School of Medicine, Emory University, 1639 Pierce Drive, WMB 308 Atlanta, GA 30322, United States.
出版信息
Curr Cardiol Rev. 2019;15(2):136-144. doi: 10.2174/1573403X15666181205110624.
Abstract
Atrial fibrillation is the most common sustained cardiac arrhythmia. The scope and impact of atrial fibrillation are wide; it can affect cardiac function, functional status, and quality of life, and it confers a stroke risk. There are sex differences in atrial fibrillation across the scope of the disease process, from epidemiology and causative mechanisms to management and outcomes. The approach to management of atrial fibrillation differs between women and men, and there are sex differences in response to medical therapy and catheter ablation. There are many gaps in our knowledge of the gender differences in atrial fibrillation, and many opportunities for future research.
摘要
心房颤动是最常见的持续性心律失常。心房颤动的范围和影响广泛；它可影响心脏功能、功能状态和生活质量，并会带来中风风险。在心房颤动整个疾病过程中，从流行病学、致病机制到管理和预后，均存在性别差异。心房颤动的管理方法在男性和女性之间有所不同，并且在药物治疗和导管消融的反应方面也存在性别差异。我们对心房颤动性别差异的认识存在许多空白，未来有很多研究机会。
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本文引用的文献
1
Hypertensive Disorders of Pregnancy and 10-Year Cardiovascular Risk Prediction.妊娠高血压疾病与 10 年心血管风险预测。
J Am Coll Cardiol. 2018 Sep 11;72(11):1252-1263. doi: 10.1016/j.jacc.2018.05.077.
2
Sex differences in complications of catheter ablation for atrial fibrillation: results on 85,977 patients.心房颤动导管消融并发症的性别差异：85977例患者的结果
J Interv Card Electrophysiol. 2018 Dec;53(3):333-339. doi: 10.1007/s10840-018-0416-1. Epub 2018 Jul 30.
3
Lifetime Risk of Atrial Fibrillation by Race and Socioeconomic Status: ARIC Study (Atherosclerosis Risk in Communities).按种族和社会经济地位划分的房颤终生风险：ARIC 研究（社区动脉粥样硬化风险）。
Circ Arrhythm Electrophysiol. 2018 Jul;11(7):e006350. doi: 10.1161/CIRCEP.118.006350.
4
Cardiac tamponade in catheter ablation of atrial fibrillation: German-wide analysis of 21 141 procedures in the Helios atrial fibrillation ablation registry (SAFER).心脏压塞在心房颤动导管消融中的应用：Helios 心房颤动消融登记研究（SAFER）中 21141 例德国范围内的分析。
Europace. 2018 Dec 1;20(12):1944-1951. doi: 10.1093/europace/euy131.
5
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Circ J. 2018 Aug 24;82(9):2259-2268. doi: 10.1253/circj.CJ-17-1358. Epub 2018 Jun 8.
6
Gender-related Differences in Management of Nonvalvular Atrial Fibrillation in an Asian Population.亚洲人群非瓣膜性心房颤动管理中的性别差异
Korean Circ J. 2018 Jun;48(6):519-528. doi: 10.4070/kcj.2017.0389.
7
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8
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J Am Heart Assoc. 2018 May 13;7(10):e007584. doi: 10.1161/JAHA.117.007584.
9
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10
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