From the Department of Nuclear Medicine, Institut Curie, PSL Research University, Paris, France.
Clin Nucl Med. 2019 Feb;44(2):e107-e109. doi: 10.1097/RLU.0000000000002413.
Malignant conjunctival melanoma is a rare tumor. A 46-year-old woman with a history of locally recurrent left conjunctival melanoma was followed by F-FDG PET/CT. Four years after the local recurrence treated by orbital exenteration, the follow-up PET/CT scan showed an incidental intense FDG uptake mass infiltrating the gallbladder associated with a low uptake of an infracentimetric pulmonary nodule. The patient was completely asymptomatic with no sign of local recurrence. Laparoscopic cholecystectomy was performed, and histopathologic findings were consistent with gallbladder metastasis of melanoma. After almost 2 years of immunotherapy, the patient is still in complete response.
结膜恶性黑色素瘤是一种罕见的肿瘤。一位 46 岁的女性,左眼结膜黑色素瘤局部复发病史,行 F-FDG PET/CT 随访。局部复发经眶内容剜除术后 4 年,随访 PET/CT 扫描显示胆囊内一处偶然的 FDG 摄取强烈的肿块浸润,同时伴有一个亚厘米肺结节的低摄取。患者完全无症状,无局部复发的迹象。行腹腔镜胆囊切除术,组织病理学检查结果与黑色素瘤的胆囊转移一致。免疫治疗近 2 年后,患者仍处于完全缓解状态。