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99mTc-HYNIC-TOC 与 18F-FDG PET/CT 探测到的伴有生长抑素受体闪烁显像的混合性血管滤泡性淋巴结增生症

A Mixed Variant of Castleman Disease Detected by Somatostatin Receptor Scintigraphy with 99mTc-HYNIC-TOC and 18F-FDG PET/CT.

机构信息

From the Department of Nuclear Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College Hospital; and Beijing Key Laboratory of Molecular Targeted Diagnosis and Therapy in Nuclear Medicine, Beijing 100730, People's Republic of China.

出版信息

Clin Nucl Med. 2019 Feb;44(2):164-166. doi: 10.1097/RLU.0000000000002411.

DOI:10.1097/RLU.0000000000002411
PMID:30516666
Abstract

A 50-year-old woman was found with a hypervascular abdominal mass in the right lower quadrant in contrast-enhanced CT. Somatostatin receptor scintigraphy with Tc-HYNIC-TOC showed positivity of the abdominal mass and detected additional lesion with moderate increased radioactivity in the right axilla. In F-FDG PET/CT, both of the lesions were FDG-avid. A hypermetabolic node in the right supraclavicular fossa was also noted. The histopathological examination of the abdominal mass after surgical resection revealed Castleman disease, a mixed hyaline vascular and plasma cell variant. The right axillary and supraclavicular lesions were considered involvement of Castleman disease.

摘要

一位 50 岁女性在增强 CT 中发现右下腹部有一个富血管性腹部肿块。Tc-HYNIC-TOC 生长抑素受体闪烁显像显示腹部肿块呈阳性,并在右侧腋窝发现了另一个放射性中度增加的病灶。在 F-FDG PET/CT 中,两个病灶均摄取 FDG。还注意到右锁骨上窝有一个高代谢性结节。腹部肿块切除术后的组织病理学检查显示为Castleman 病,为混合性透明血管和浆细胞型。右侧腋窝和锁骨上病变被认为是 Castleman 病的累及。

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