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2型糖尿病的治疗困境——改善并维持β细胞功能及胰岛素敏感性

Therapeutic dilemmas in type II diabetes mellitus--improving and maintaining beta-cell and insulin sensitivity.

作者信息

Karam J H

出版信息

West J Med. 1988 Jun;148(6):685-90.

PMID:3051674
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1026207/
Abstract

These discussions are selected from the weekly staff conferences in the Department of Medicine, University of California, San Francisco. Taken from transcriptions, they are prepared by Drs Homer A. Boushey, Professor of Medicine, and David G. Warnock, Associate Professor of Medicine, under the direction of Dr Lloyd H. Smith, Jr, Professor of Medicine and Associate Dean in the School of Medicine. Requests for reprints should be sent to the Department of Medicine, University of California, San Francisco, School of Medicine, San Francisco, CA 94143.

摘要

这些讨论内容选自加利福尼亚大学旧金山分校医学系的每周员工会议。它们取自会议记录,由医学教授荷马·A·布希博士和医学副教授大卫·G·沃诺克博士在医学教授兼医学院副院长小劳埃德·H·史密斯博士的指导下整理而成。如需转载,请寄至加利福尼亚大学旧金山分校医学院医学系,地址为:旧金山,CA 94143。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/66f2/1026207/a96525d272d1/westjmed00142-0070-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/66f2/1026207/a96525d272d1/westjmed00142-0070-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/66f2/1026207/a96525d272d1/westjmed00142-0070-a.jpg

相似文献

1
Therapeutic dilemmas in type II diabetes mellitus--improving and maintaining beta-cell and insulin sensitivity.2型糖尿病的治疗困境——改善并维持β细胞功能及胰岛素敏感性
West J Med. 1988 Jun;148(6):685-90.
2
Hypoglycemia: a pitfall of insulin therapy.低血糖:胰岛素治疗的一个陷阱。
West J Med. 1983 Nov;139(5):688-95.
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Waldenström's macroglobulinemia.华氏巨球蛋白血症
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Biochemical and clinical aspects of amyloidosis.
West J Med. 1987 Jul;147(1):65-70.
5
Liver transplantation--the first 25 years.肝移植——最初的25年
West J Med. 1988 Sep;149(3):316-21.
6
Fulminant hepatic failure.暴发性肝衰竭
West J Med. 1988 Nov;149(5):586-91.
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Pheochromocytoma--recent advances in diagnosis and treatment.嗜铬细胞瘤——诊断与治疗的最新进展
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Idiopathic pulmonary fibrosis.
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引用本文的文献

1
Intracellular traffic of newly synthesized proteins. Current understanding and future prospects.新合成蛋白质的细胞内运输。当前的认识与未来展望。
J Clin Invest. 1989 Mar;83(3):739-51. doi: 10.1172/JCI113952.

本文引用的文献

1
Receptor and postreceptor defects contribute to the insulin resistance in noninsulin-dependent diabetes mellitus.受体及受体后缺陷促成了非胰岛素依赖型糖尿病中的胰岛素抵抗。
J Clin Invest. 1981 Oct;68(4):957-69. doi: 10.1172/jci110350.
2
Dietary protein intake and the progressive nature of kidney disease: the role of hemodynamically mediated glomerular injury in the pathogenesis of progressive glomerular sclerosis in aging, renal ablation, and intrinsic renal disease.膳食蛋白质摄入量与肾脏疾病的进展特性:血流动力学介导的肾小球损伤在衰老、肾切除及原发性肾脏疾病所致进行性肾小球硬化发病机制中的作用
N Engl J Med. 1982 Sep 9;307(11):652-9. doi: 10.1056/NEJM198209093071104.
3
The defective glucose sensitivity of the B cell in non insulin dependent diabetes. Improvement after twenty hours of normoglycaemia.
非胰岛素依赖型糖尿病中B细胞葡萄糖敏感性缺陷。血糖正常20小时后的改善情况。
Metabolism. 1982 Feb;31(2):139-42. doi: 10.1016/0026-0495(82)90125-1.
4
Increase in insulin response after treatment of overt maturity-onset diabetes is independent of the mode of treatment.显性成年型糖尿病治疗后胰岛素反应的增加与治疗方式无关。
Diabetologia. 1980 Jan;18(1):23-8. doi: 10.1007/BF01228297.
5
Absorption kinetics and action profiles of mixtures of short- and intermediate-acting insulins.
Diabetologia. 1984 Dec;27(6):558-62. doi: 10.1007/BF00276967.
6
Diminished B cell secretory capacity in patients with noninsulin-dependent diabetes mellitus.非胰岛素依赖型糖尿病患者B细胞分泌能力降低。
J Clin Invest. 1984 Oct;74(4):1318-28. doi: 10.1172/JCI111542.
7
Effects of physical training and diet therapy on carbohydrate metabolism in patients with glucose intolerance and non-insulin-dependent diabetes mellitus.体育锻炼和饮食疗法对糖耐量异常和非胰岛素依赖型糖尿病患者碳水化合物代谢的影响。
Diabetes. 1984 Apr;33(4):311-8. doi: 10.2337/diab.33.4.311.
8
New concepts in the pathogenesis and treatment of noninsulin-dependent diabetes mellitus.
Am J Med. 1983 Jan 17;74(1A):52-81. doi: 10.1016/0002-9343(83)90654-x.
9
Partial pancreatectomy in the rat and subsequent defect in glucose-induced insulin release.大鼠部分胰腺切除术及随后葡萄糖诱导的胰岛素释放缺陷。
J Clin Invest. 1983 Jun;71(6):1544-53. doi: 10.1172/jci110910.
10
Insulin-dependent regulation of insulin receptor concentrations: a direct demonstration in cell culture.胰岛素受体浓度的胰岛素依赖性调节:细胞培养中的直接证明。
Proc Natl Acad Sci U S A. 1974 Jan;71(1):84-8. doi: 10.1073/pnas.71.1.84.