Terrier Jean, Reny Jean-Luc, Fontana Pierre
Service de médecine interne générale, HUG, 1211 Genève 14.
Service d'angiologie et hémostase, HUG, 1211 Genève 14.
Rev Med Suisse. 2018 Dec 5;14(630):2193-2197.
Antithrombotic drugs are regularly prescribed for the treatment and prevention of venous or arterial thromboembolic events. The co-prescription of an anticoagulant and antiplatelet drug is frequent in daily practice even if evidence of benefit associated with such an association is limited, while the increased bleeding risk is well established. The aim of this article is to review the situations where antiplatelet drugs are indicated in patients already treated with long-term anticoagulants. The perspective of adapting and personalizing antithrombotic therapy according to each patient's characteristics is also discussed.
抗血栓药物常用于治疗和预防静脉或动脉血栓栓塞事件。在日常实践中,抗凝药和抗血小板药联合使用的情况很常见,尽管这种联合用药的获益证据有限,但其出血风险增加却是明确的。本文旨在综述在已接受长期抗凝治疗的患者中使用抗血小板药物的情况。还讨论了根据每位患者的特点调整和个性化抗血栓治疗的观点。