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复合牛骨填充牙槽窝的保存:一项单盲随机临床试验

Preservation of Dental Sockets Filled with Composite Bovine Bone. A Single-Blind Randomized Clinical Trial.

作者信息

Natale Júnior Vail, Souza Francisley Ávila, Vedovatto Eduardo, Nishioka Renato Sussumu, Poli Pier Paolo, Carvalho Paulo Sérgio Perri de

机构信息

Implant Dentistry Post-Graduation Program, School of Dentistry and Research Center SLMANDIC - Faculdade de Medicina e Odontologia e Centro de Pesquisas Odontológicas São Leopoldo Mandic, Campinas, SP, Brazil.

Department of Surgery and Integrated Clinic, Araçatuba Dental School, UNESP - Universidade Estadual Paulista, Araçatuba, SP, Brazil.

出版信息

Braz Dent J. 2018 Nov-Dec;29(6):583-591. doi: 10.1590/0103-6440201802064.

Abstract

The purpose of this study was to evaluate the preservation of alveolar dimensions in human fresh extraction sockets filled with a composite bovine bone graft by means of design of single-blind randomized clinical trial. Forty participants had monoradicular teeth extracted (one teeth in each participant), and after were randomly divided into 2 groups: individuals whose fresh sockets were filled with the composite heterologous bone graft (Biomaterial Group), or with blood clot (Control Group). After extraction, the fresh sockets were measured at their greatest mesiodistal (MD) and bucco-lingual/palatal (BL/P) distance. Primary closure of the soft tissue was performed with a fibro-mucosal plug. After 120 post-operative days, the re-entry procedure was performed and the largest MD and BL/P measurements were again obtained to calculate the remodeling of the alveolar bone measured in percentage. In the biomaterial group, a percentage reduction of 1.62% and 3.29% in the MD and BL/P dimensions was observed 120 days after the extractions, whereas a reduction of 4.97% and 7.18% in the MD and BL/P dimensions occurred in the control group. There was a statistically significant difference (p<0.05) between the two groups for the bucco-palatal and mesiodistal measurements in the maxilla. In view of the results obtained, it can be concluded that composite bovine bone graft limited but did not impede alveolar bone remodeling.

摘要

本研究的目的是通过单盲随机临床试验设计,评估在填充复合牛骨移植物的人类新鲜拔牙窝中牙槽尺寸的保存情况。40名参与者拔除了单根牙(每位参与者一颗牙),拔牙后随机分为两组:新鲜拔牙窝填充复合异种骨移植物的个体(生物材料组),或填充血凝块的个体(对照组)。拔牙后,在新鲜拔牙窝的最大近远中(MD)和颊舌/腭(BL/P)距离处进行测量。用纤维粘膜栓进行软组织的一期缝合。术后120天,进行再次切开手术,再次获得最大的MD和BL/P测量值,以计算以百分比表示的牙槽骨重塑情况。在生物材料组中,拔牙后120天观察到MD和BL/P尺寸分别降低了1.62%和3.29%,而对照组的MD和BL/P尺寸分别降低了4.97%和7.18%。在上颌骨的颊腭和近远中测量中,两组之间存在统计学显著差异(p<0.05)。鉴于所获得的结果,可以得出结论,复合牛骨移植物限制了但并未阻碍牙槽骨重塑。

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