Bratt H, Skjeldestad F E, Cullberg Valentin K
Department of Obstetrics and Gynecology, Trondheim University Hospital, Norway.
Acta Obstet Gynecol Scand. 1988;67(3):247-51. doi: 10.3109/00016348809004214.
A randomized prospective trial of three copper IUDs, Nova-T, MLCu375 and MLCu250, including 200 of each, is presented. Insertion was done at the hospital outpatient clinic on normally menstruating women and on women in puerperio. Follow-up was scheduled after 12, 24 and 36 months. Pregnancy rates were low for all 3 models. Pearl indices after 3 years were 0.5, 0.9 and 0.8 for Nova-T, MLCu375 and MLCu250 respectively (NS). Abnormal bleeding and/or pain was the most frequent termination cause. Minor differences in the termination rates because of abnormal bleeding and/or pain were found and are discussed. The continuation rates based on all medically relevant IUD removals were 74%, 73% and 81% after 3 years for Nova-T, MLCu375 and MLCu250 respectively. No important difference in clinical performance between the three copper IUDs could be demonstrated.
本文介绍了一项对三种铜宫内节育器（Nova-T、MLCu375和MLCu250）进行的随机前瞻性试验，每种节育器各200例。在医院门诊为正常月经的妇女和产后妇女放置节育器。随访安排在12个月、24个月和36个月后进行。所有三种型号的妊娠率都很低。三年后的Pearl指数，Nova-T、MLCu375和MLCu250分别为0.5、0.9和0.8（无显著性差异）。异常出血和/或疼痛是最常见的终止使用原因。发现并讨论了因异常出血和/或疼痛导致的终止使用率的微小差异。基于所有与医学相关的宫内节育器取出情况，三年后的持续使用率，Nova-T、MLCu375和MLCu250分别为74%、73%和81%。三种铜宫内节育器在临床性能上未显示出重要差异。
