Dicker D, Feldberg D, Yeshaya A, Peleg D, Karp M, Goldman J A
Department of Obstetrics and Gynecology, Golda Meir Medical Center, (Hasharon Hospital), Petah Tikva, Israel.
Am J Obstet Gynecol. 1988 Oct;159(4):800-4. doi: 10.1016/s0002-9378(88)80139-x.
Ninety-eight insulin-dependent diabetic pregnancies underwent monitoring by means of 978 biophysical profiles from 28 weeks' gestation until parturition. Only 2.9% of the 978 tests had abnormal results (score less than or equal to 7). When performed within 2 days before birth, a normal biophysical profile predicted the 1-minute Apgar score to be normal in 92% and 5-minute Apgar score in 99%. When all biophysical profiles ever performed were included, the predictive value improved to 100%. The baby's first cry within 1 minute after birth was predicted in 95%. Furthermore, the predictive value of a normal biophysical profile regarding the absence of ominous intrapartum cardiotocographic patterns was excellent (95%). The specificity was in general good (80% to 90%), but the predictive value of abnormal test results and sensitivity were almost without exception poor. It seems that the very low rate of abnormal biophysical profiles indicates that obstetric interventions were made immediately after the occurrence of the first sign of fetal jeopardy; thus improved results were obtained.
98例胰岛素依赖型糖尿病孕妇从妊娠28周直至分娩期间接受了978次生物物理评分监测。在这978次检查中，只有2.9%的结果异常（评分小于或等于7分）。在出生前2天内进行检查时，正常的生物物理评分预测1分钟阿氏评分正常的概率为92%，5分钟阿氏评分正常的概率为99%。若将所有进行过的生物物理评分都纳入分析，预测值可提高到100%。预测出生后1分钟内婴儿首次啼哭的准确率为95%。此外，正常生物物理评分对于产时无不良胎心监护图形的预测价值极佳（95%）。特异性总体良好（80%至90%），但异常检查结果的预测值以及敏感性几乎无一例外都很差。生物物理评分异常率极低似乎表明，在出现胎儿窘迫的首个迹象后立即进行了产科干预，从而取得了更好的结果。
