Nagayama Y, Namura Y, Tamura T, Muso R
2nd Department of Internal Medicine, Kyoto University Hospital, Japan.
Ann Allergy. 1988 Oct;61(4):289-95.
Prostaglandin E1 was intravenously injected daily for 4 weeks to three patients with lupus nephritis accompanied by severe nephrotic syndrome. Histologic examination revealed diffuse proliferative or membranous glomerulonephritis. Proteinuria decreased markedly 1 year after the treatment with improvement in hypoproteinemia in all three patients. Five years later, the conditions of three cases ameliorated further.
对三名伴有严重肾病综合征的狼疮性肾炎患者，每天静脉注射前列腺素E1，持续4周。组织学检查显示为弥漫性增殖性或膜性肾小球肾炎。治疗1年后，蛋白尿明显减少，所有三名患者的低蛋白血症均有改善。五年后，三例患者的病情进一步好转。
