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Recovery from acute virus infection. Role of cytotoxic T lymphocytes in the elimination of lymphocytic choriomeningitis virus from spleens of mice.

作者信息

Lehmann-Grube F, Moskophidis D, Löhler J

机构信息

Heinrich-Pette-Institut für Experimentelle Virologie und Immunologie, Hamburg, Federal Republic of Germany.

出版信息

Ann N Y Acad Sci. 1988;532:238-56. doi: 10.1111/j.1749-6632.1988.tb36343.x.

DOI:10.1111/j.1749-6632.1988.tb36343.x
PMID:3052209
Abstract
摘要

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The effect of lymphocytic choriomeningitis virus-induced suppression of the delayed-type hypersensitivity reaction on virus clearance and pathogenicity.淋巴细胞性脉络丛脑膜炎病毒诱导的迟发型超敏反应抑制对病毒清除及致病性的影响
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Mechanism of recovery from acute virus infection. IV. Questionable role of mononuclear phagocytes in the clearance of lymphocytic choriomeningitis virus from spleens of mice.
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Selection of genetic variants of lymphocytic choriomeningitis virus in spleens of persistently infected mice. Role in suppression of cytotoxic T lymphocyte response and viral persistence.持续性感染小鼠脾脏中淋巴细胞性脉络丛脑膜炎病毒基因变体的选择。在抑制细胞毒性T淋巴细胞反应和病毒持续性中的作用。
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The immune response of the mouse to lymphocytic choriomeningitis virus. V. High numbers of cytolytic T lymphocytes are generated in the spleen during acute infection.小鼠对淋巴细胞性脉络丛脑膜炎病毒的免疫反应。V. 急性感染期间脾脏中产生大量细胞毒性T淋巴细胞。
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