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系统性红斑狼疮与重症肌无力并存:一例罕见的多自身免疫病病例

Coexistence of Systemic Lupus Erythematosus and Myasthenia Gravis: An Unusual Case of Polyautoimmunity.

作者信息

García-Alfonso Carolina, Bernal-Macías Santiago, García-Pardo Yulieth, Millán Sonia Patricia, Díaz María-Claudia

机构信息

Unidad de Neurología, Hospital Universitario San Ignacio, Bogotá, Colombia.

Departamento de Medicina Interna, Hospital Universitario San Ignacio, Bogotá, Colombia.

出版信息

Reumatol Clin (Engl Ed). 2020 Nov-Dec;16(6):502-505. doi: 10.1016/j.reuma.2018.08.013. Epub 2018 Dec 3.

Abstract

The relevance of polyautoimmunity, defined as the presence of 2or more autoimmune diseases in the same individual, is one of the issues not yet elucidated in medical practice. The coexistence of myasthenia gravis (MG) and systemic lupus erythematosus (SLE) is a clinical challenge due to the possible differential diagnoses of muscle involvement in patients with SLE. We present the case of a patient who came to the emergency room of Hospital Universitario San Ignacio in Bogotá, Colombia, with a previous diagnosis of SLE, who developed acute weakness in the context of a systemic infection, with a clinical and electrophysiological diagnosis of MG.

摘要

多自身免疫(定义为同一个体存在两种或更多自身免疫性疾病)的相关性是医学实践中尚未阐明的问题之一。重症肌无力(MG)和系统性红斑狼疮(SLE)并存是一项临床挑战,因为SLE患者的肌肉受累可能存在鉴别诊断。我们报告一例患者,该患者此前被诊断为SLE,因系统性感染出现急性肌无力,在哥伦比亚波哥大圣伊格纳西奥大学医院急诊室就诊,临床及电生理诊断为MG。

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