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淋巴增生性疾病和免疫抑制治疗后的造口形成。

Stoma formation after lymphoproliferative disorders and immunosuppression therapy.

作者信息

Fulham Juliette, Plucinski Micaela

机构信息

Coloplast Nurse and Stoma Nurse Specialist, University College London Hospitals NHS Foundation Trust.

Lymphoma Nurse Specialist, University College London Hospitals NHS Foundation Trust.

出版信息

Br J Nurs. 2018 Dec 13;27(22):S20-S26. doi: 10.12968/bjon.2018.27.22.S20.

Abstract

Post-transplant lymphoproliferative disorders (PTLD) are lymphomas that may arise in organ, bone marrow or stem cell transplant recipients who are taking immunosuppressive drugs to prevent rejection of the transplant. The likelihood of developing PTLD depends on the type of transplant. PTLD is a potentially severe complication of post-transplant treatment, with an uncertain prognosis. Lymphoproliferative disorders can also occur in people taking immunosuppressants for inflammatory bowel disease. This article will explore PTLD and discuss the experience of caring for patients who developed lymphoproliferative conditions and required emergency stoma formation. The emotional and physical impact of surgery upon these patients, who have already experienced a protracted treatment journey, will be explored. Implications for practice for the lymphoma team and stoma nurse specialists involved with the care of these patients will also be considered.

摘要

移植后淋巴细胞增生性疾病(PTLD)是一种淋巴瘤,可能发生在接受器官、骨髓或干细胞移植的患者身上,这些患者正在服用免疫抑制药物以防止移植排斥反应。发生PTLD的可能性取决于移植的类型。PTLD是移植后治疗的一种潜在严重并发症,预后不确定。淋巴细胞增生性疾病也可能发生在因炎症性肠病而服用免疫抑制剂的人群中。本文将探讨PTLD,并讨论护理发生淋巴细胞增生性疾病并需要紧急造口的患者的经验。将探讨手术对这些已经经历了漫长治疗过程的患者所产生的情绪和身体影响。还将考虑对参与这些患者护理的淋巴瘤团队和造口护士专家的实践意义。

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