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Multicenter study of skin rashes and hepatotoxicity in antiretroviral-naïve HIV-positive patients receiving non-nucleoside reverse-transcriptase inhibitor plus nucleoside reverse-transcriptase inhibitors in Taiwan.台湾地区初治的HIV阳性患者接受非核苷类逆转录酶抑制剂加核苷类逆转录酶抑制剂治疗时皮疹和肝毒性的多中心研究。
PLoS One. 2017 Feb 21;12(2):e0171596. doi: 10.1371/journal.pone.0171596. eCollection 2017.
2
Identification of a novel and severe pattern of efavirenz drug-induced liver injury in South Africa.南非依法韦仑药物性肝损伤一种新型严重模式的鉴定。
AIDS. 2016 Jun 1;30(9):1483-5. doi: 10.1097/QAD.0000000000001084.
3
Pharmacogenetics of plasma efavirenz exposure in HIV-infected adults and children in South Africa.南非成人和儿童HIV感染者血浆依法韦仑暴露的药物遗传学
Br J Clin Pharmacol. 2015 Jul;80(1):146-56. doi: 10.1111/bcp.12590. Epub 2015 May 28.
4
Cutaneous adverse drug reactions caused by FDCAs - we need to characterise and manage them urgently.由二氟尼柳引起的皮肤药物不良反应——我们急需对其进行特征描述并加以管理。
S Afr Med J. 2013 Nov;103(11):815. doi: 10.7196/samj.7479.
5
Annular erythema and photosensitivity as manifestations of efavirenz-induced cutaneous reactions: a review of five consecutive cases.以环形红斑和光敏反应为表现的依非韦伦所致皮肤反应：5例连续病例回顾
J Antimicrob Chemother. 2013 Dec;68(12):2871-4. doi: 10.1093/jac/dkt287. Epub 2013 Jul 12.
6
[Cutaneous drug-reactions to nevirapine: study of risk factors in 101 HIV-infected patients].
Ann Dermatol Venereol. 2005 Dec;132(12 Pt 1):970-4. doi: 10.1016/s0151-9638(05)79559-4.
7
A method for estimating the probability of adverse drug reactions.一种估算药物不良反应概率的方法。
Clin Pharmacol Ther. 1981 Aug;30(2):239-45. doi: 10.1038/clpt.1981.154.

Treatment can be continued for mild cutaneous reactions associated with efavirenz.

作者信息

Isaacs Thuraya, Ngwanya Reginald Mduzumile, Dlamini Sipho, Peter Jonny, Lehloenya Rannakoe

机构信息

Division of Dermatology, Department of Medicine, University of Cape Town, Cape Town, South Africa.

Division of Infectious Diseases and HIV Medicine, Department of Medicine, University of Cape Town, Cape Town, South Africa; Combined Drug Allergy Clinic, Groote Schuur Hospital, Cape Town, South Africa.

出版信息

J Allergy Clin Immunol Pract. 2019 May-Jun;7(5):1676-1678. doi: 10.1016/j.jaip.2018.11.041. Epub 2018 Dec 6.

DOI:10.1016/j.jaip.2018.11.041
PMID:30529062
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7045143/
Abstract
摘要